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3. Peng, Dandan. , et al. "Targeting TGF-β signal transduction for fibrosis and cancer therapy." Molecular cancer 21.1(2022):104. 4. Larson, Christopher , et al. "TGF-beta: a master immune regulator." Expert Opi...
TGFbeta biology in cancer progression and immunotherapy.Nat Rev Clin OncolJan 2021;18(1):9-34.doi:10.1038/s41571-020-0403-1. 4.Nixon BG, Gao S, Wang X, Li MO. TGFbeta control of immune responses in cancer: a holistic immuno-oncology perspective.Nat Rev ImmunolNov 15 2022.doi:10.1038...
The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway. Dev Cell. 2010 Dec 14; 19(6):831-44.10. Zhang YE. Non-Smad pathways in TGF-beta signaling. Cell Res. 2009; 19(1):128-139.11. Massagué J. TGFbeta in Cancer. Cell. 2008;134(...
转化生长因子 (Transforming growth factor beta，TGF-β) 是一类多功能的细胞因子，可由多种组织细胞产生。TGF-β 信号通路是由众多成员的多功能细胞因子，与相应的受体、细胞内信号转导分子组成的通路，能影响疾病发生和发展，调节基因的转录，控制着细胞周期，影响细胞的增殖、分化、黏附、转移和凋亡。值得注意的是...
colorectal cancerdisease-free survivaloverall survivalprogression-free survivalsurrogate endpointsDespite significant advances in the treatment of hematological malignancies over the previous decades, morbidity and mortality from theses disorders still remain high. New discoveries in the pathways involved in the ...
具有口服生物活性的 TGF-beta 信号通路的激活剂,具有神经保护作用。 TGF-beta/Smad 化合物库 100+ 种 TGF-β/SMAD 信号相关小分子化合物,是 TGF-β/SMAD 信号通路相关药物筛选和疾病研究的有用工具。 TGF-β 受体抑制剂/激动剂 TGF-β 受...
转化生长因子 (Transforming growth factor beta,TGF-β) 是一类多功能的细胞因子,可由多种组织细胞产生。TGF-β 信号通路是由众多成员的多功能细胞因子,与相应的受体、细胞内信号转导分子组成的通路,能影响疾病发生和发展,调节基因的转录,控制着细胞周期,影响细胞的增殖、分化、黏附、转移和凋亡。值得注意的是,TGF...
TGF beta R2 ELISA Kit for cell culture supernatants, plasma, and serum samples. Pre-coated 96-well strip microplate kit. 15 pg/ml sensitivity. Human TGF beta Pathway Phosphorylation Array C1 Detects 8 phosphorylated proteins in human samples. Suitable for all liquid sample types but intended for...
1.Massagué J. TGFbeta in Cancer.Cell. 2008 Jul 25;134(2):215-30. doi: 10.1016/j.cell.2008.07.001. PMID:18662538; PMCID: PMC3512574. 2.Vander Ark A, et al. TGF-βreceptors: In and beyond TGF-β signaling. Cell Signal. 2018 Dec;52:112-120.doi: 10.1016/j.cellsig.2018.09.002...