6. Schmierer B, Hill CS. TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility. Nat Rev Mol Cell Biol. 2007;8(12):970-982. 7. Papoutsoglou P, Coulouarn C, et al. Transforming Growth Factor-Beta (TGFβ) Signaling Pathway in ...
转化生长因子 (Transforming growth factor beta,TGF-β) 是一类多功能的细胞因子,可由多种组织细胞产生。TGF-β 信号通路是由众多成员的多功能细胞因子,与相应的受体、细胞内信号转导分子组成的通路,能影响疾…
9. Varelas X, Wrana JL, et al. The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway. Dev Cell. 2010 Dec 14; 19(6):831-44. 10. Zhang YE. Non-Smad pathways in TGF-beta signaling. Cell Res. 2009; 19(1):128-139. 11. Massagué J...
9. Varelas X, Wrana JL, et al. The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway. Dev Cell. 2010 Dec 14; 19(6):831-44. 10. Zhang YE. Non-Smad pathways in TGF-beta signaling. Cell Res. 2009; 19(1):128-139. 11. Massagué J...
9. Varelas X, Wrana JL, et al. The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway. Dev Cell. 2010 Dec 14; 19(6):831-44. 10. Zhang YE. Non-Smad pathways in TGF-beta signaling. Cell Res. 2009; 19(1):128-139. ...
第一篇 TGF-β Signaling doi:10.3390/biom10030487 Activation of latent TGF-β. The TGF-β/SMAD signaling pathway. Internalization and intracellular sorting of TGF-β receptors. Schematic representation of structure of the SMAD proteins. The TGF-β non-SMAD signaling pathways. 第二篇 TGF-β rec...
14. B B Cazac, et al. and Jürgen Roes. TGF-β receptor controls B cell responsiveness and induction of IgA in vivo.Immunity. 2000 Oct;13(4):443-51. 15. Vanessa Zaiatz-Bittencourt,et al. Vanessa, David K. Finlay, and Clair M. Gardiner. Canonical TGF-β signaling pathway represses ...
Integration of the TGF-β/Smad pathway into the signalling network has taken on added importance as it substantially contributes to elicit the plethora of cell- and tissue-specific effects of TGF-β. Introduction Transforming growth factor-β (TGF-β) is a secreted cytokine that exerts an ...
The TGF beta signaling pathway plays an important role in the development, homeostasis, and repair of most tissues in organisms. All immune cell lineages, including B-cell, T-cell, and dendritic cells as well as macrophages, secrete TGF beta, which...
145 TGF-Beta-Signaling Pathway Inactivation and Cell Cycle Deregulation in Human Gastric Cell Lines and elf+/-/smad4+/- Tissues. Lopa Mishra, Kirti Shetty, Lynt Johnson, Eugene Volpe, Stephen Evans, Thomas Fishbein, Yi Tang, Varalakshmi Katuri Transforming growth factor-beta (TGF-b) can ...