The classical target organs for parathyroid hormone (PTH) are the bone and kidneys. In uremia, however, numerous studies have shown that PTH may also affect the function of a number of nonclassical organs and tissues besides the bone and kidney, including the brain, heart, smooth muscles, ...
target organ托福 生词本:添加笔记: 有奖纠错 | 划词 英汉-汉英词典 靶器官 近义、反义、联想词 近义词 n. organ 英语例句库 1.These results suggest that early neonatal hopocalcemia appears to be related to a transient lack of response to PTH of thetargetorgans, disorderedvitamin Dmetabolism andhyp...
In some cases, where the target organ has a number of changes in addition to the treatment-related change, we may opt to review all of the target organs in all dose groups, but only for the specific treatment-related change. We find that by reviewing the target organ in all dose groups...
Interestingly, organs in this (spleen, MLN and situation AdIiPB1 BAL) 30 days after s.c + i.n. vaccinated mice had more antigen-specific cells in the spleen compared to NP vaccinated mice, whereas similar numbers were found in MLNs, and more antigen-specific cells were recovered...
In this study, we searched for potential target genes involved in breast cancer dissemination to distant organs using in silico transcriptomic analyses of primary tumors and metastases. We found that integrin alpha5 (ITGA5) is expressed at high levels in bone metastases compared to non-bone metasta...
These biochemical changes reflect PTH resistance at both the kidney and skeleton sites of action. Administration of exogenous PTH fails to elicit normal responses at either or both of these target organs.doi:10.1007/978-1-4612-4758-6_4Arnold S. Brickman...
Downstream targets of GATA3 in the vestibular sensory organs of the inner ear Dev. Dynam., 238 (2009), pp. 3093-3102 Google Scholar Bates et al., 2015 D. Bates, M. Machler, B.M. Bolker, S.C. Walker Fitting linear mixed-effects models using lme4 J. Stat. Softw., 67 (2015), ...
The kidney has the second highest level of mitochondria and oxygen use after the heart and is, thus, one of the most energy necessitating organs in the human body [3,6]. Mitochondria are intracellular organelles that are crucial in the generation of adenosine triphosphate (ATP), the regulation...
Although mINDY is an interesting candidate for improving these conditions, inhibition of mINDY would likely need to be specifically targeted to individual organs, such as the liver, in order to avoid off-target effects in the brain. While there are no genetic association studies linking SLC13A5 ...
Thus, by mimicking the human organs the virtual organs can be created and studied for effect of drug (Figure 4). In 2011, Safety Evaluation Ultimately Replacing Animal Testing (SEURAT) program was initiated in Europe to develop alternative safety tests for cosmetics and chemicals (http://www....