hormone,secretory substance carried from one gland or organ of the body via the bloodstream to more or less specific tissues, where it exerts some influence upon the metabolism of the target tissue. Normally, various hormones are produced and secreted by the endocrine glands (seeendocrine system)...
Thyrotrophin-releasing hormone (TRH) is a hypothalamic tripeptide, synthesised by, stored within and released from the hypothalamus. It stimulates the synthesis and release of thyroid-stimulating hormone (TSH) and prolactin (PRL) from the anterior pituitary gland. In hyperthyroidism administration of ...
Thyrotropin-releasing hormone (TRH) is the most proximal component of the hypothalamic-pituitary-thyroid axis that regulates thyroid hormone synthesis. Since transcripts for members of this axis were detected in cultured normal human skin cells and since human hair follicles (HFs) respond to stimulation...
USA; 2Department of Pharmacology, Weill Cornell Medical College, New York, NY, USA Thyrotropin-releasing hormone (TRH) is a neuropeptide that initiates its effects in mice by interacting with two G-protein-coupled receptors, TRH receptor type 1 (TRH-R1) and TRH receptor type 2 (TRH-R2). ...
Erzsebet Gaspar,Celine Hardenbicker,Eniko Bodo.Thyrotropin releasing hormone (TRH): a new player in human hair-growth control.The FASEB Journal. 2010Gaspar E, Hardenbicker C, Bodo E, Wenzel B, Ramot Y, Funk W, et al. Thyrotropin releasing hormone (TRH): a new player in human hair-growth...
Ectopic expression of thyrotropin releasing hormone (TRH) receptors in liver modulates organ function to regulate blood glucose by TRH. Nat Genet 1996; 12:274-9. [PMID 8589718]Wolff G, Mastrangeli A, Heinflink M, Falck-Pedersen E, Gershengorn MC, and Crystal RG. Ectopic expression of ...
The first one was identical to that previously found for intact GH3 cells. The present data show the existence of specific nuclear binding sites for TRH, establish their characteristics and suggest a possible nuclear site of action for that peptide hormone.FBournaudDGourdjiSMongonguA...