近日,来自美国希望之城国家医疗中心血液学与造血细胞移植科的Jianhua Yu与Michael A. Caligiuri共同在Cell Stem Cell期刊发表题为Human anti-PSCA CAR macrophages possess potent antitumor activity against pancreatic cancer(人类抗PSCA CAR...
Dean M. Cancer stem cells: implications for cancer causation and therapy resistance. Discov Med. 2005; 5 :278–282. [ PubMed ]Dean M. Cancer stem cells: implications for cancer causation and therapy resistance. Discov Med. 2005;5:278-82....
resistance, indicating that targeting Notch could be a novel therapeutic approach to the treatment for cancer by overcoming drug resistance of cancer cells. ... Z Liu,F Fan,A Wang,... - 《Journal of Cancer Research & Clinical Oncology》 被引量: 136发表: 2014年 Can middle-school science te...
uPAR+ cells exhibited multi-drug resistance, high clonogenic activity, and co-expression of the putative cancer stem cell markers CD44 and MDR1 in all of the SCLC cell lines examined. 2.3.2 Sphere formation in culture Primary cancer cells can be propagated in spheroid cultures (Reynolds & ...
随着这些研究的进一步发展,未来可能会有更多基于这些发现的临床试验,以测试这种新型CAR T细胞治疗在更广泛的癌症类型中的有效性和安全性。这标志着我们在使用基因和细胞疗法对抗最顽固的疾病方面迈出了重要的一步。(4月10日Nature“How to supercharge...
These cells are known as the cancer stem cells marked by the presence of surface biomarkers, multi-drug resistance pumps and deregulated self-renewal pathways (SRPs). They have a crucial role in provoking cancer cells leading to tumorigenesis and its progressive metastasis. Cancer stem cells (...
Cancer Stem Cell News is an online resource that curates the top research publications and reviews about cancer progenitor cells and cancer stem cells.
stem cells are rare immortal cells within a tumour that can both self-renew by dividing and give rise to many cell types that constitute the tumour, and can therefore form tumours. Such cells have been found in various types of human tumours and might be attractive targets for cancer ...
TSCs tumor stem cells WIF1 Wnt inhibitory factor 1 Key words Cancer stem cells Cancer therapy CSC marker CSC-targeted mechanism Resistance Hedgehog Notch Wnt CSC niche Quiescent state miRNA expression Apoptosis DifferentiationCited by (0)Peer review under responsibility of Institute of Materia Medica, ...
3. Su, S., Lei, A., Wang, X., Lu, H., Wang, S., Yang, Y., Li, N., Zhang, Y., and Zhang, J. (2022). Induced CAR-Macrophages as a Novel Therapeutic Cell Type for Cancer Immune Cell Therapies. Cells...