因此，丝盘虫成为了一种诱人的模型生物，使研究人员能够了解辐射耐受的基本过程，以及指导DNA修复、程序化细胞死亡及其抗癌能力的潜在机制。近期，这项研究的研究结果发表在《PLOS Biology》上，题为“Upregulation of DNA repair genes and cell extrusion underpin the remarkable radiation resistance of Trichoplax adhae...
The article reports that according to a study by researcher Rene Bernard and colleagues which is published in the journal "Cell," when the gene MED12 was switched off, the cells in a variety of cancers became resistant to a range of anticancer drugs....
因此,丝盘虫成为了一种诱人的模型生物,使研究人员能够了解辐射耐受的基本过程,以及指导DNA修复、程序化细胞死亡及其抗癌能力的潜在机制。 近期,这项研究的研究结果发表在《PLOS Biology》上,题为“Upregulation of DNA repair genes and ...
14.Rau, K.-M.; Kang, H.-Y.; Cha, T.-L.; A Miller, S.; Hung, M.-C. The mechanisms and managements of hormone-therapy resistance in breast and prostate cancers. Endocr. Relat. Cancer 2005, 12, 511–532. [CrossRef] 15.Van Duursen, M.B.M.; Nijmeijer, S.; De Morree, E...
Cancer is a group of diseases in which cells divide continuously and excessively. Cell division is tightly regulated by multiple evolutionarily conserved cell cycle control mechanisms, to ensure the production of two genetically identical cells. Cell cycle checkpoints operate as DNA surveillance mechanisms...
第二篇,综述文章“Non-Coding RNAs Steering the Senescence-Related Progress, Properties, and Application of Mesenchymal Stem Cells”,于2021年1月19号投稿,2021年2月12号接收,用时三周多。 第三篇,论著文章“The absence of PTEN in breast cancer is a driver of MLN4924 resistance”,于2021年2月13号投...
9. Uchibori, K., et al., Brigatinib combined with anti-EGFR antibody overcomes osimertinib resistance in EGFR-mutated non-small-cell lung cancer. Nat Commun, 2017. 8: p. 14768. 10. Shaw, A.T., et al., ...
[19] Yang X, Wang H, et al. Rewiring ERBB3 and ERK signaling confers resistance to FGFR1 inhibition in gastrointestinal cancer harbored an ERBB3-E928G mutation. Protein Cell. 2020 Dec.(IF:14.872)浙江大学医学院/转化医学研究院闵军霞团队 ...
transformation, progression and metastatization, the biology of cancer stem cells and their immunological properties, the mechanisms undergoing the epithelial-to mesenchymal (EMT) transition and tumor dormancy, their relationship with immune functions and the mechanisms undergoing cancer resistance to ...
Cell Biologists: Explore cutting-edge research on cellular mechanisms involved in cancer progression and therapy resistance, critical for developing new treatments. Geneticists: Delve into genetic mutations,oncogenes, and genome-wide studies, and discover the role of genetics in personalized cancer treatmen...