Pinilla S, Alt E, Abdul Khalek FJ, Jotzu C, Muehlberg F, Beckmann C and Song YH: Tissue resident stem cells produce CCL5 under the influence of cancer cells and thereby promote breast cancer cell invasion. Cancer Lett 284: 80‑85, 2009....
Compared with bone marrow-derived cells, ASCs as tissue-resident stem cells are locally adjacent to breast cancer cells and may interact with tumor cells directly. Here, we demonstrate that ASCs cause the cancer to grow significantly faster when added to a murine breast cancer 4T1 cell line....
While T-cell responses to cancer immunotherapy have been avidly studied, long-lived memory has been poorly characterized. In a cohort of metastatic melanoma survivors with exceptional responses to immunotherapy, we probed memory CD8+ T-cell responses acr
Tissue resident mesenchymal stem cells (MSCs) are known to participate in tissue regeneration that follows cell turnover, apoptosis, or necrosis. It has been long known that aging impedes an organism's repair/regeneration capabilities. In order to study the age associated changes, the molecular cha...
The Sty-containing protein Sox2 initially was known to regulate the self-renewal of the mouse and human embryonic stem cells (ESCs). It is also important f... K Liu,B Lin,M Zhao,... - 《Cellular Signalling》 被引量: 217发表: 2013年 Cellular signaling in normal and cancerous stem cell...
conception, but have also been linked to various immunopathologies and cancer. The proliferative, secretory, and regenerative phases of the menstrual cycle affect the proliferative capacity of immune cells [45]. In cell culture experiments, the proliferation of peripheral blood mononuclear cells (PBMCs...
[14]. Cardiac stem cell therapy could be a practical option to selectively activate macrophages. Vagnozzi et al.have observed that, following an ischemia–reperfusion injury, the intracardiac injection of bone marrow mononuclear cells (MNCs) promotes the recruitment of CX3CR1+and CCR2+macrophages ...
Oligo-β-(1 → 3)-glucans: impact of thio-bridges on immunostimulating activities and the development of cancer stem cells. J. Med. Chem. 57, 8280–8292 (2014). Article CAS PubMed Google Scholar GBD 2019 Diseases and Injuries Collaborators.Global burden of 369 diseases and injuries in ...
They also express a number of markers associated with mesenchymal stem cells, including CD44, CD73, CD105 and CD146 [64]. Of note is that cells continue to express PDGFRβ after they become myofibroblasts, and that, conversely, pericytes may express collagen I transcript even in healthy ...
TRMcells can directly modulate cardiomyocyte function To evaluate the hypothesis that TRMcells can significantly alter the electrical properties of coupled cardiomyocytes compared to non-TRMcells, we performed co-culture studies with induced pluripotent stem cell–derived cardiomyocytes (iPSC-CMs) with an ...