During lytic or latent infection of sensory neurons with herpes simplex virus type 1 (HSV-1) there are significant changes in the expression of voltage-gated Na + channels, which may disrupt the transmission of pain information. HSV-1 infection can also evoke the secretion of various pro-...
While it has recently been shown that lactate anion acts on chloride channel, less is known regarding a potential effect on the voltage-gated sodium channel (Na(v)) of skeletal muscle. The electrophysiological properties of muscle Na(v) were studied in the absence and presence of lactate (10...
Post-transcriptional Regulation of Voltage-Gated Sodium Channel 1.8 (Nav1.8): A Key Underlying Mechanism of Neuropathic Pain Pathogenesis. 来自 掌桥科研 喜欢 0 阅读量: 21 作者: S Ruangsri 摘要: Neuropathic pain is a chronic disease that commonly arises following injury to the peripheral nervous ...
Seeing the forest through the trees comprehensive inference on individual mating patterns in a mixed stand of Quercus robur and Q. petraea 热度: 相关推荐 SeeingtheForestthroughtheTrees:towardsaUnifiedViewon PhysiologicalCalciumRegulationofVoltage-GatedSodiumChannels FilipVanPetegem, † *PaoloA.Lobo...
Regulation of the cardiac voltage-gated sodium channel Nav1.5 : regulation of Nav1.5 by ubiquitin-protein ligases of the Nedd4/Nedd4-like family and characterisation of two novel mutations in the gene encoding Nav1.5 (SCN5A) implicated in ...
Regulation of Voltage-Dependent Sodium Channels 来自 国家科技图书文献中心 喜欢 0 阅读量: 18 作者: S Cukierman 摘要: No Abstract available for this article. 关键词: Fezes Ancylostoma Necator Paleopatologia###Base de dados DOI: 10.1007/s002329900071 被引量: 55 年份: 1996 收藏...
Structure and function of voltage-gated sodium and calcium channels The primary structures of the Na+ channel a-subunits from several species have now been deduced from cDNA sequences, and complete primary structures of all... Catterall,A William - 《Current Opinion in Neurobiology》 被引量: 505...
The intracellular COOH-terminal domain of the β(1)-subunit appeared to play an essential role in the regulation of Na(v)1.8 expression and gating. 展开 关键词: voltage-gated sodium channels, nociception DOI: 10.1152/jn.00107.2011 被引量: 45 ...
Tetrodotoxin (TTX), an inhibitor of voltage-gated sodium channels, was used to block action potentials for one hour before and during the stimulation and recovery times. When slices were treated with TTX (1 mM), stimulation no longer resulted in increased SUMOylation (Fig. S1b). Thus, the...
Levitan I.B. 1994. Modulation of ion channels by protein phosphorylation and dephosphorylation.Annu. Rev. Physiol.56, 193–212. ArticlePubMedCASGoogle Scholar Scheuer T. 1994. Structure and function of voltage-gated sodium channels: Regulation by phosphorylation.Biochem. Soc. Trans.22, 479–82....