Neighbor of BRCA1 (Nbr1) is a conserved autophagy receptor that provides cargo selectivity to autophagy. The four-tryptophan (FW) domain is a signature domain of Nbr1, but its exact function remains unclear. Here, we show that Nbr1 from the filamentous f
F. CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription. Genes. Dev. 6, 439–453 (1992). Article CAS PubMed Google Scholar Zinszner, H. et al. CHOP is implicated...
The preservation of the D2 domain among species and within nearly all receptor-like PTPs indicates that it probably serves an important physiological function. Its structural integrity is important for stability of the PTPR as a whole. Also, there is the possibility that D2 might be involved ...
LAP(Human Leucine aminopepridase) ELISA Kit人亮氨酰氨基肽酶Multi-class antibodies规格:48T TMIGD1英文名称: 跨膜TMIGD1蛋白抗体0.1ml PGGT1B英文名称: 香叶烯基转移酶1β抗体0.2ml Anti-TEM8/FITC荧光素标记内皮标志物8抗体IgGMulti-class antibodies规格:0.2ml ...
The glomerular cells with positive signals were numerous, compared with the number of infiltrating monocyte-macrophages identified with a monoclonal antibody. These results indicate that mature TGF-beta and TGF-beta-LAP are localized in association with the matrix components of GBM or mesangium, and ...
Western blot analysis of protein extracts from normal rat ovaries and human and porcine mature CL with 3B5 antibody showed six distinct bands migrating between ~92 and ~48 kDa (lanes 2, 4 and 6, Fig. 4; see also Fig. 5A). Although weak, some LHR immunoreactivity was also detected in ...
(Fig.1d). Since the lophophorates are closely related to molluscs and annelids1,2,4,6,41, the homology of the lophophore with other spiralian ciliary bands is plausible. However, the lophophore cilia are significantly different in structure and function from those of other spiralian ciliary...
2). Expression of each isoforms was induced in U2OS FT pgLAP5.2 NudCD1-GFP cells by the addition of doxycycline for 24 hours, and the cells were fixed prior to immunofluorescence labelling using a GFP antibody, and the nucleus was visualized using DAPI to allow DNA coloration. Imaging of...
Complementary negative EV markers include the cell surface protein Gpm1, the actin binding protein Apb1, and the intracellular proteins Apr1, Cpy1, Lap41, Sod2 and Lpd1. We are confident that these positive and negative EV marker proteins will be valuable in future investigations on C. ...
Madalinsky for antibody purification, R. Foisner for LAP2α/LAP2β and actin antibodies, P. Kovarik for Phospho-Erk antibodies, P. Collas and E. Watrin for hCAP-D2/huEg7 antibodies, and K. Nasmyth for discussions and generous support. Work in the lab of E.O. was supported by grants...