eBPAG1 and -2 epithelial bullous pemphigoid antigen 1 and 2, respectively HD hemidesmosome FN-III type III fibronectin LRR leucine-rich repeat LAP/LERP leucine-rich repeat and PDZ domain NHK normal human keratinocytes Ab antibody HA hemagglutinin GFP green fluorescent protein BD DNA binding domain ...
These results suggest that Hsp60 has significantly higher avidity for anti-Hsp60 antibody and LAP than Internalin B. In summary, LAP is identified as an alcohol acetaldehyde dehydrogenase and binding of recombinant E. coli to Caco-2 cells or rLAP to Hsp60 protein was found to be highly ...
W. Activation of an unfolded protein response during differentiation of antibody-secreting B cells. J. Biol. Chem. 277, 49047–49054 (2002). Article CAS PubMed Google Scholar Fernandez, P. M. et al. Overexpression of the glucose-regulated stress gene GRP78 in malignant but not benign ...
The TP53BP1, which is a tumor protein P53 binding protein 1 that enhances TP53-mediated activation, plays a principal role in the response to DNA damage and controls the checkpoint signaling in mitosis including control of the G2/M checked point (Huret, 2006b; Tumor Protein, 2016; Wang et...
antibody binding. The immunostained sections were further stained with uranyl acetate for 3 min and lead citrate for 1 min, and then observed under a transmission electron microscope (Hitachi, H-7650, H-7650 control Ver. 01. 10, EMIP Ver. 05. 04). The number of gold particles per ...
particularly if the cells are immature. TGF-beta 1 also inhibits proliferation and stimulates apoptosis of B cells, and plays a role in controlling the expression of antibody, transferrin and MHC class II proteins on immature and mature B cells. As for myeloid cells, TGF-beta 1can inhibit the...
As used herein, the term “anti-TFPI antibody” refers to an antibody having binding specificity against the human TFPI protein as well as fragments and variants of the human TFPI protein. Anti-TFPI antibodies presented herein can be IgG2 antibodies and include anti-TFPI IgG2 monoclonal antibodie...
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59898. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate...
(Fig.3c). The N-terminal tail of CtAms1_1 is anchored at the surface of CtAms1_3 before contacting β-sheet 2 of the FW domain and inserting the first two glycine residues into a pocket on the FW domain. The binding interface with the N-terminal tail of CtAms1 buries a solvent-...
Antibody supershift assays were used to identify individual C/EBP family members present in the EMSA complexes. There are three DNA-binding species in the nuclear proteins of control-treated lungs (PBS): a low, but detectable, level of C/EBPα/β heterodimers, heterodimers between C/EBPβ ...