I modular polyketide synthase (PKS) gene cluster in Streptomyces ambofaciens, enabling the identification of a unique structural class of polyketides with promising antitumor activity.41 LAL regulators, which were encoded on a plasmid, were under the control of a strong constitutive ermE※ promoter....
The ability of whole cells to catalyse multistep reactions, often yielding synthetically demanding compounds later used by industrial biotech or pharma, makes them an indispensable tool of synthetic chemistry. The complex reaction network employed by cellular catalysts and the still only moderate predictiv...