Ppar.gamma. Agonist for treatment of bone diseaseThe present invention relates to the ppar.gamma. Agonist, particularly known as int 131 (I): To provide a method of treating osteoporosis or bone disease, including the use of a compound.ランフェアー デニス...
It has now been discovered that the PPARγ agonist INT131 (also known as CHS-131) is effective for treating blood cancers including leukemia and myeloma. In one aspect, the present invention provides methods of treating leukemia or myeloma and symptoms thereof. The methods typically involve admini...
The effects of PPAR- gamma agonist pioglitazone on renal ischemia/reperfusion injury in rats. J Surg Res 2013;182:176-84. B Reel,M Guzeloglu,A Bagriyanik,... - 《Journal of Surgical Research》 被引量: 55发表: 2013年 Ameliorative Effects of GW1929, a Nonthiazolidinedione PPARγ Agonist,on...
Inhibition of in Vivo Glioma Growth and Invasion by Peroxisome Proliferator-Activated Receptor γ Agonist Treatment The peroxisome proliferator-activated receptor gamma (PPARgamma), a member of the nuclear hormone receptor family, represents a possible new target in glio... C Grommes,GE Landreth,M ...
A novel PPAR gamma agonist monascin's potential application in diabetes prevention. Food and Function, 5, 1334-1340... W Hsu,T Pan - 《Food & Function》 被引量: 0发表: 2014年 Monascin and ankaflavin act as natural AMPK activators with PPARα agonist activity to down-regulate nonalcoholic...
A Novel Partial Agonist of Peroxisome Proliferator-Activated Receptor-{gamma} (PPAR{gamma}) Recruits PPAR{gamma}-Coactivator-1{alpha}, Prevents Triglyceride ... B Elke,S Astride,F Angele,... - 《Molecular Endocrinology》 被引量: 243发表: 2006年 A novel insulin sensitizer acts as a coligand...
Google Share on Facebook PPARG (redirected fromPPARgamma) PPARG A gene on chromosome 3p25 that encodes a member of the nuclear receptor family of ligand-activated transcription factors, which heterodimerise with the retinoic X receptor (RXR) to regulate gene expression. PPARG binds peroxisome prolif...
Pioglitazone, a PPAR gamma Agonist, Upregulates the Expression of Caveolin-1 and Catalase, Essential for Thyroid Cell Homeostasis: A Clue to the Pathogenesis of Hashimoto's Thyroiditis 来自 万方 喜欢 0 阅读量: 7 摘要: Background: Peroxisome proliferator-activated rece 年份: 2016 ...
Peroxisome Proliferator-activated Receptor α (PPARα) Agonist Treatment Reverses PPARα Dysfunction and Abnormalities in Hepatic Lipid Metabolism in Ethan... Proper function of the peroxisome proliferator-activated receptor alpha (PPARalpha) is essential for the regulation of hepatic fatty acid metabolism...
Mifepristone, a PPAR gamma agonist, has also been shown to protect against cerebral ischemia [33]. PPAR gamma also activates the (SOCS) suppressor of cytokine signalling [34]. Increased SOCS 3 expression is associated with reduced IL-6 and TGF-1 expression, oedema formation, and vacuolization,...