Heterogeneous and polyclonal population of B cells in the thymic GCs of MG patients[61–63] Cytokines involved in B-cell growth and differentiation (IL-6) increased in MG[64] B-cell-stimulating cytokines induce polyclonal B-cell activation, and positive correlations were observed between IgG and...
These results support a hypothesis that severe periodontitis, in this select patient population, occurs as a consequence of B-cell hyperreactivity. The data further suggest the possibility that the polyclonal B-cell activators in dental plaque organisms may initiate this disease by nonspecifically ...
Refer to a homogenous population of antibodies that are produced by a single clone of plasma B cells. Produced by different clones of plasma B cells. Produced by the same clone of plasma B cells. Production does not require hybridoma cell lines. Production requires hybridoma cell lines. A hete...
sera, we’ll have a mixture of ten different antibodies produced from ten different B-cell clones, hence the term polyclonal. Figure 1. A polyclonal antibody preparation actually contains a mixture of different antibodies derived from different B-cell clones. Now imagine that, instead of collecting...
cell population maintenancecell-cell adhesioncell aggregationregulation of postsynaptic density protein 95 clusteringpositive regulation of synaptic vesicle clusteringcerebral cortex developmentregulation of myelinationregulation of Rho protein signal transductionpositive regulation of muscle cell differentiationprotein ...
Produced by different clones of plasma B cells. Produced by the same clone of plasma B cells. Production does not require hybridoma cell lines. Production requires hybridoma cell lines. A heterogeneous antibody population. A homogenous antibody population. Interact with different epitopes on the same...
IL-6 also activates naive CD4+ T cells to become helper T cells. Later, helper T-cell plays the leading role in B cell proliferation, B cell class switching, and maturation of B cells into immunoglobulin-secreting plasma cells. Furthermore, IL-6 supports chronic inflammation and aut...
cell differentiation regulation of oligodendrocyte progenitor proliferation establishment of protein localization to plasma membrane negative regulation of canonical Wnt signaling pathway neuroligin clustering involved in postsynaptic membrane assembly neuronal stem cell population maintenance regulation of postsynaptic ...
(3) The CLL leukemic cell population is a mixed one, some cells carrying normal, some abnormal karyotypes. It is unlikely that T cells contributed to any significant number of normal metaphases, first because EBV is a specific B-cell stimulator,15 and second, very few T cells were present...
cell differentiation regulation of oligodendrocyte progenitor proliferation establishment of protein localization to plasma membrane negative regulation of canonical Wnt signaling pathway neuroligin clustering involved in postsynaptic membrane assembly neuronal stem cell population maintenance regulation of postsynaptic ...