Gatto, F.; Cagliani, R.; Catelani, T.; Guarnieri, D.; Moglianetti, M.; Pompa, P.; Bardi, G. PMA-Induced THP-1 Macrophage Differentiation is Not Impaired by Citrate-Coated Platinum Nanoparticles. Nanomaterials 2017, 7, 332. [CrossRef] [PubMed]...
相对于人外周血单核细胞（PBMC），THP-1更易在实验室中培养和扩增，且具有更稳定的基因背景，不存在PB...
LPS 致病作用的关键在于 其通过激活 Toll 样受 体 4 (toll like receptor 4,TLR4)跨膜信号通路, 活化以单核/巨噬细胞为代表的宿主免疫细胞,促进细胞因子和炎症介质的过度释放, 引 起全身失控性炎症级联反应,TNF-α、IL-6 在·论著·[文章编号]1000-8861(2013)02-0121-05分化诱导剂 PMA 对 THP-1 源性...
图1 两种PMA方案诱导THP-1分化为M0 巨噬细胞后相关基因表达的变化 Fig.1 The change of the related genes expression in M0 macrophages induced by two PMA methods 噬细胞接受IL-4刺激后MRC-1上调了3.58±0.02倍, 学和麻省波士顿儿童医院的科学家观察到IL-4激活 ± γ 显著高于100 ng/mL方案组的2.34 ...
Phorbol 12-myristate 13-acetate (PMA) is commonly used to activate protein kinase C (PKC) and a Standard Reagent for THP1 cell differentiation into macrophages-type cells.
(P<005vs0ng/ml).ConclusionThe10ng/mlPMAcaninduceTHP1cellstodifferentiatetowardsmacrophage,whichprovidesabasisforPMAinduceddifferentiationofTHP1cellsintomacrophagemodels.Keywords:phorbolmyristateacetate;THP1cells;CD14;CD11b 巨噬细胞(macrophage)是一类由血液中单核细胞分化而来的固有免疫细胞 [1] ,是机体固有免疫...
PMA诱导人单核细胞白血病细胞株THP-1细胞表面标志物CD14和CD11b的表达
Phorbol 12-myristate 13-acetate (PMA) 属于佛波酯类天然产物,是一种 PKC、SphK、NF-κB 的激活剂。Phorbol 12-myristate 13-acetate 可诱导 THP1 细胞分化。 规格价格库存数量 1 mg¥ 436现货 5 mg¥ 1,050现货 10 mg¥ 1,770现货 25 mg¥ 3,730现货 ...
PMA-induced differentiation of myeloid cells is accompanied by inhibition of uPA-PAI-1 internalization/degradation and the down-regulation of alpha 2-MR. ... M Conese,F Blasi - Biological chemistry Hoppe-Seyler 被引量: 222发表: 1995年 Regulation of ApoE receptor proteolysis by ligand binding Tw...
PMA-Induced THP-1 Macrophage Differentiation is Not Impaired by Citrate-Coated Platinum Nanoparticles The innate immune system consists of several complex cellular and molecular mechanisms. During inflammatory responses, blood-circulating monocytes are driv... G Francesca,C Roberta,C Tiziano,... - 《Na...