We demonstrate that plant-derived exosome-like nanoparticles (ELNs) are taken up by the gut microbiota and contain RNAs that alter microbiome composition and host physiology. Ginger ELNs (GELNs) are preferentially taken up by Lactobacillaceae in a GELN lipid-dependent manner and contain microRNAs ...
Plant-derived exosome-like nanoparticles for microRNA delivery in cancer treatment Chun Yi Linzhu Lu Xuefei Tian Drug Delivery and Translational Research(2025) SmithHunter: a workflow for the identification of candidate smithRNAs and their targets ...
To overcome these limitations, we considered plant-derived vesicles (PDVs) for efficient delivery of small RNAs to the TME. Vesicles with similarities to mammalian EVs can be generated from plants. These vesicles, which range from 50 to 1000 nanometers in size, are biocompatible, can be taken...
Interspecies communication between plant and mouse gut host cells through edible plant derived exosome‐like nanoparticles Interspecies communication between plant and mouse gut host cells through edible plant derived exosome-like nanoparticles . Molecular Nutrition & Food Ressearch... J Mu,X Zhuang,Q ...
Preparation and isolation process of plant-derived nanovesicles. (PELNVsplant exosome-like nanovesicles,UCultracentrifugation,AGO2Argonaute 2,mRNAmessenger RNA,PBSphosphate-buffered saline,GAPDHglyceraldehyde-3-phosphate dehydrogenase.) (Copyright [26]) ...
Techniques and Applications of Animal- and Plant-Derived Exosome-Based Drug Delivery System Moreover, this review also highlights the research progresses on plant-derived exosomes in determining their commonalities with and distinctions from animal-... F Man,J Wang,R Lu - 《Journal of Biomedical Na...
Interspecies communication between plant and mouse gut host cells through edible plant derived exosome-like nanoparticles. Mol Nutr Food Res. 2014;58(7):1561–73. Article CAS PubMed PubMed Central Google Scholar Rahimi Ghiasi M, Rahimi E, Amirkhani Z, R. Salehi, leucine-rich repeat-containing...
The use of plant-derived exosome-like nanoparticles as a delivery system of CRISPR/Cas9-based therapeutics for editing long non-coding RNAs in cancer colon... and safety of using plant-derived exosome-like nanoparticles as nanocarriers for delivering CRISPR/Cas9-based therapeutics to target colon ca...
Indeed, plant-derived exosome-like nanoparticles are also biocompatible and biodegradable, as are exosomes of animal origin, while having several distinct advantages. PEVs can be isolated in large amounts, thus making plants the raw materials of choice to isolate safe and effective vehicles for the...
Plant-derived chemicals have numerous biological functions [1]. These account for about 40% of currently marketed medications [2]. Many factors influence the ability of plant-derived chemicals to provide therapeutic effects in the human body. Most plant-derived chemicals have a low water solubility...