Don leaves-derived exosome-like nanovesicles (CLDENs) were isolated from apoplastic fluid. CLDENs were membrane structured vesicles with a particle size of 75.51卤10.19nm and a surface charge of 21.8mV. CLDENs exhibited excellent stability, tolerating multiple enzymatic digestions, resisting extreme pH...
In addition, this was verified not only in ginger-derived nanovesicles, but also in tomato-derived nanovesicles. Gorevic et al. found that tomato-derived nanovesicles were also taken up byFusobacterium nucleatumand that this uptake process was also dependent on lipid components [14]. When lipids ...
Yam-derived exosome-like nanovesicles stimulate osteoblast formation and prevent osteoporosis in mice. J Controll Release Off J Controll Release Soc. 2023;355:184–98. Article CAS Google Scholar Xu XH, Yuan TJ, Dad HA, Shi MY, Huang YY, Jiang ZH, Peng LH. Plant exosomes as novel ...
Cucumber-derived exosome-like vesicles and plantcrystals for improved dermal drug delivery. Pharmaceutics. 2022;14(3):476. doi:10.3390/pharmaceutics14030476 72. Cui WW, Ye C, Wang KX, et al. Momordica. charantia-derived extracellular vesicles-like nanovesicles protect cardiomyocytes against radiation ...
Plant exosome-like nanovesicles, being innately replete with bioactive lipids, proteins, RNA, and other pharmacologically active molecules, offer unique morphological and compositional characteristics as natural nanocarriers. Furthermore, their compelling physicochemical traits underpin their modulative role in ...
kinase (MAPK) signaling pathway in dendritic cells, enhancing their tolerance and preventing excessive inflammatory responses, thus offering protection against ulcerative colitis [40]. Moreover, garlic chives-derived nanovesicles have shown the ability to inhibit the activation of the NOD-like receptor ...
Characterization of grapefruit-derived nanovesicles Vesicles were isolated from 400 mL of grapefruit juice by sequential ultracentrifugation according to the purification protocol for edible plant-derived exosome-like nanoparticles described earlier16 with some modifications. In order to characterize grapefruit...
Alfieri, M., Leone, A. & Ambrosone, A. Plant-derived nano and microvesicles for human health and therapeutic potential in nanomedicine.13, 498–518 (2021). Dad, H. A., Gu, T. W., Zhu, A. Q., Huang, L. Q. & Peng, L. H. Plant exosome-like nanovesicles: emerging therapeutics...
we isolated and purified the exosome-like particles fromA. annua, which were characterized by nano-scaled and membrane-bound shape and hence termed artemisia-derived nanovesicles (ADNVs). Remarkably, the vesicles demonstrated to inhibit tumor growth and boost anti-tumor immunity in a mouse model of...
et al. Targeted Drug Delivery to Intestinal Macrophages by Bioactive Nanovesicles Released from Grapefruit. Mol. Ther. 22, 522–534 (2014). Article CAS PubMed PubMed Central Google Scholar Liu, Y. et al. Enhancing oral delivery of plant-derived vesicles for colitis. J. Control Rel. 357,...