Plant cell culture technologyPlant-derived exosomes-like nanovesicles (PDENs) have been found to be advantageous in disease treatment and drug delivery, but research on their biogenesis, compositional analysis, and key marker proteins is still in its infancy, which limits the standardized production ...
such as drug carriers, targeted therapy, disease diagnosis, and treatment. Nevertheless, further clinical development is hampered by the complex extraction process, potential side effects, limited yield, and high cost. In recent years, plant-derived EVs (PDEVs) isolated...
(sRNAs) were reported as a new class of functional components in decoctions. However, the mechanisms by which sRNAs survive heat treatment of the decoction and enter cells are unclear. Previous studies showed that plant-derived exosome-like nanoparticles (ELNs), which we call botanosomes, could...
As in animals, cell–cell communication plays a pivotal role in male–female recognition during plant sexual reproduction. Prelaid peptides secreted from the female reproductive tissues guide pollen tubes towards ovules for fertilization. However, the el
insulin-like growth factor (IGF), epidermal growth factor (EGF), IL-8, IL-6, and IL-11, which are carried by exosome to influence EMT; interact with cancer cells to increase cancer proliferation, migration, invasion; induce immunosuppression and chemotherapy resistance; and remold ECM [42]. ...
H. et al. Engineering exosome-like nanovesicles derived from Asparagus cochinchinensis can inhibit the proliferation of hepatocellular carcinoma cells with better safety profile. Int. J. Nanomedicine 2021, 16, 1575–1586. Article Google Scholar Tong, L. J.; Hao, H. N.; Zhang, Z.; Lv, Y....
As in animals, cell–cell communication plays a pivotal role in male–female recognition during plant sexual reproduction. Prelaid peptides secreted from the female reproductive tissues guide pollen tubes towards ovules for fertilization. However, the el
Ginger, derived from the rhizome ofZingiber officinaleRosc., is consumed as a spice and also used as an alternative medicine for a range of disorders like cold, fever, as well as many digestive tract problems like diarrhea and dyspepsia [117]. Studies have also shown that ginger and its act...
Keywords: extracellular vesicles;plant-derived EVs;therapeutic applications;anti-cancer efficacy;drug delivery
Hollow-fiber bioreactor production of extracellular vesicles from human bone marrow mesenchymal stromal cells yields nanovesicles that mirrors the immuno-modulatory antigenic signature of the producer cell. Stem Cell Res. Ther. 2021, 12, 127. [Google Scholar] [CrossRef] [PubMed] Publisher’s Note:...