In summary, we have isolated exosomes and produced cancer-cell-membrane-exosome-mimetic nanovesicles that both show parent cell targeting. Additionally, homotypic targeting was obtained preferentially by the mimetic nanovesicles.Gabrielle AbbottChuanbin Mao...
4B). In addition, we evaluated the effect of exosome-mimetic nanovesicles in mice without partial hepatectomy. Because no liver injury is present in mice without partial hepatectomy, hepatocytes were in the G0 phase, in which mitotic division is rare or absent. We found that exosome-mimetic NVs...
M1 Macrophage-Derived Exosome-Mimetic Nanovesicles with an Enhanced Cancer Targeting Ability Extracellular vesicles (EVs) have been found to be effective therapeutic drug delivery vehicles in a wide range of human diseases, including cancer and neu... S Baek,M Jeon,NJ Han,... - 《Acs Applied ...
In this research, brain-targeted exosome-mimetic cell membrane nanovesicles (CMNVs) were designed to enhance the delivery of therapeutic oligonucleotides into the brain. First, CMNVs were produced by extrusion with isolated C6 cell membrane fragments. Then, CMNVs were decorated with choleste...
Could bioengineered exosome-mimetic nanovesicles be an efficient strategy for the delivery of chemother- apeutics? Nanomedicine (Lond). 2014;9(2):177-80.Jang SC, Gho YS. Could bioengineered exosome-mimetic nanovesicles be an efficient strategy for the delivery of chemotherapeutics? Nanomedicine 2014;...
Immunomodulatory Effects of MDA-MB-231-derived Exosome Mimetic Nanovesicles on CD4 T Cell Linedoi:10.14744/ejmo.2024.64067Oztatlici, MustafaOzdemir, Alper TungaOztatlici, HulyaKucukhuyuk, SerifeOzdemir, Rabia Bilge OzgulOrhan, HilmiOzbilgin, Kemal...
therapeutic exosomesAbstract Issues associated with upscaling exosome production for therapeutic use may be overcome through utilizing artificial exosomes. Cellヾerived mimetic nanovesicles (M㎞Vs) ar... 查看全部>>doi:10.1002/pmic.201800161John Wiley & Sons, LtdPROTEOMICS...
A method for manufacturing nanovesicles is disclosed. The exosome-mimicking nanovesicle is a nano-sized vesicle contained in the filtrate of adult stem cells that are sequentially passed through two or more membrane filters of different sizes, from the largest filter to the smallest filter. ....
Disclosed are a composition for promoting angiogenic activity comprising exosome-mimetic nanovesicles derived from adult stem cells, which improve problems of existing exosome derived from adult stem cells, as active ingredients, and a method for manufacturing exosome-mimetic nanovesicles derived from adult...
Targeted Delivery of Mesenchymal Stem Cell-Derived Bioinspired Exosome-Mimetic Nanovesicles with Platelet Membrane Fusion for Atherosclerotic Treatmentdoi:10.2147/IJN.S452824Jiang, YuYu, MiaoSong, Zhi-FengWei, Zhi-YaoHuang, JiQian, Hai-YanInternational Journal of Nanomedicine...