Plant exosomes as novel nanoplatforms for microrna transfer stimulate neural differentiation of stem cells in vitro and in vivo. Nano Lett. 2021;21(19):8151–9. Article CAS PubMed Google Scholar Kim DK, Rhee WJ. Antioxidative effects of carrot-derived nanovesicles in cardiomyoblast and ...
Plant-derived nanovesicles (PDNVs) have been proposed as a major mechanism for the inter-kingdom interaction and communication, but the effector components enclosed in the vesicles and the mechanisms involved are largely unknown. The plantArtemisia annuais known as an anti-malaria agent that also e...
Indeed, plant-derived exosome-like nanoparticles are also biocompatible and biodegradable, as are exosomes of animal origin, while having several distinct advantages. PEVs can be isolated in large amounts, thus making plants the raw materials of choice to isolate safe and effective vehicles for the...
Plant-derived nano and microvesicles have being surprisingly almost neglected for a long time. In fact, nano-sized vesicles in plants have been observed in the '60s4,5, earlier than animal exosomes6,7, but their biological role remained largely unexplored. In the last decade, distinct classes ...
Indirect methods can be used to load exosomes as well that include endogenous methods where the progenitor cells are loaded with the therapeutic agents to passively transfer the drug into the EV during biogenesis. The cells can also become modified genetically to express the cargoes of RNAs, ...
(Foxa2) in intestinal epithelial cells, thereby influencing the secretion of exosomes to prevent insulin resistance [39]. Intriguingly, certain lipids have been found to possess anti-inflammatory properties. Digalactosydiacylglycerol (DGDG) within oats-derived nanovesicles would reduce inflammation by ...
Plant exosomes as novel nanoplatforms for microrna transfer stimulate neural differentiation of stem cells in vitro and in vivo. Nano Lett. 2021, 21, 8151–8159. [Google Scholar] [CrossRef] [PubMed] Teng, Y.; Xu, F.; Zhang, X.; Mu, J.; Sayed, M.; Hu, X.; Lei, C.; Sriwas...
Engineering exosomes as refined biological nanoplatforms for drug delivery. Acta Pharmacol. Sin. 2017, 38, 754–763. [Google Scholar] [CrossRef] [PubMed] [Green Version] Sato, Y.T.; Umezaki, K.; Sawada, S.; Mukai, S.A.; Sasaki, Y.; Harada, N.; Shiku, H.; Akiyoshi, K. ...