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However, there are risks associated with it as well, like immunogenicity and reversion to virulence. Therefore, the relentless search for alternative nanoparticles for gene delivery has led to the utilization of exosomes as a viable candidate. The similar mechanism of actions for gene transfection ...
Exosomes have been recognized for their potential as therapeutic carriers in neurodegenerative diseases due to their unique ability to transport bioactive compounds across cellular barriers and modulate various cellular processes [131,132]. Their adaptability as therapeutic agents can be classified into two ...
As a drug delivery system, exosomes outperform other delivery platforms such as lipid nanoparticles, liposomes, and polymeric nanomicelles when it comes to disease-related applications[24]. The major advantages are as follows: (1) high targeting capacity increases drug use efficiency and decreases dru...
Exosomes, a subgroup of extracellular vesicles (EVs), have been recognized as important mediators of long distance intercellular communication and are involved in a diverse range of biological processes. Because of their ideal native structure and characteristics, exosomes are promising nanocarriers for cl...
Western blotting, alternatively referred to as immunoblotting, is a method that separates and visualizes proteins using gel electrophoresis, contingent upon the characteristics of the sample or the gel, after the application of particular antibodies. In EV research, this method is commonly utilized to...
exosomes as drug carriers can improve drug inhibition and bioavailability and reduce drug side effects [71,72]. This kind of RNA nanoparticles can improve the targeting ability and deliver therapeutic drugs to specific cancer cells. It has been reported that RNA nanoparticles can be used to ...
Breast cancer (BC) is a prevalent and highly lethal cancer in females. Like other cancer types, the intricate cellular and molecular heterogeneity leads to the variation of therapeutic outcomes. The development and progression of blood vessels increase t
When compared to synthetic nanoparticles, exosomes are considered an optimal drug delivery system, as they encompass many exceptional features: remarkable biocompatibility and stability, minimal immunogenicity and toxicity, long half-life circulation, an inherent capability to target specific tissues, and the...
Theranostic small interfering RNA nanoparticles in cancer precision nanomedicine Wiley Interdisc. Rev. Nanomed. Nanobiotechnol., 12 (2) (2020), Article e1595 View in ScopusGoogle Scholar [31] X. He, G. Kuang, Y. Wu, C. Ou Emerging roles of exosomal miRNAs in diabetes mellitus Clin. Transl...