Plant-Derived Exosomal Nanoparticles Inhibit Pathogenicity of Porphyromonas gingivalisBacteriologyBiochemistryBiological SciencesImmunologyMicrobiologyMolecular BiologyOral MicrobiologyPlant exosomes protect plants against infection; however, whether edible plant exosomes can protect mammalian hosts against infection is not...
Plant-Derived Exosomal MicroRNAs Shape the Gut MicrobiotaIL-22LexAand LGG adherenceginger exosome-like nanoparticlegut microbiota compositionlipid targetingmiRNA/mRNA interactionsmall RNAtryptophan metabolitesSupplementary Figures and Supplementary Tablesdoi:10.1016/j.chom.2018.10.001Teng, Yun...
Edible plant-derived exosomal microRNAs: Exploiting a cross-kingdom regulatory mechanism for targeting SARS-CoV-2. Toxicol Appl Pharmacol. 2021;414: 115425. Article CAS PubMed PubMed Central Google Scholar Chen Q, Li Q, Liang Y, Zu M, Chen N, Canup BSB, Luo L, Wang C, Zeng L, ...
Exosomal delivery systems for therapeutic molecules have recently been considered as an alternative drug carrier system33. However, the translation of this system into the clinic is limited by major challenges, including insufficient loading efficiency34,35, poor delivery to the TME, low scalability, ...
The monocyte-derived exosomal CLMAT3 activates the CtBP2-p300-NF-kappaB Transcriptional Complex to Induce Proinflammatory cytokines in ALI. Mol Ther Nucleic Acids. 2020;21:1100–10. Article CAS PubMed PubMed Central Google Scholar Chen Z, Dong WH, Chen Q, Li QG, Qiu ZM. Downregulation of...
[45]. Furthermore, Teng et al. used experiments to validate the treatment of ali-miR 396a-5p in ginger-derived nanovesicles blocked exosomal Nsp 12/Nsp 13-mediated NF-κB activation, which subsequently prevented apoptosis and excessive inflammatory responses in lung epithelial cells. Intratracheal ...
et al. Systemic exosomal siRNA delivery reduced alpha-synuclein aggregates in brains of transgenic mice. Mov Disord. 2014;29(12):1476-85 129. Zhang H, Bai L, He J, Zhong L, Duan X, Ouyang L. et al. Recent advances in discovery and development of natural products as source for ...
2. Surface modification, drug loading, and optimal administration can enhance the therapeutic effects of PDNVs. 3. Exploring the relationship between the constituents and bioactivity of PDNVs holds potential for innovative therapeutic strategies in tissue damage repair. ...
Plant-derived nanovesicles (PDNVs) have been proposed as a major mechanism for the inter-kingdom interaction and communication, but the effector components enclosed in the vesicles and the mechanisms involved are largely unknown. The plant Artemisia annu
Plant-derived exosomal nanoparticles: potential therapeutic for inflammatory bowel disease Nanoscale Adv. (2023) X. Chen et al. Exosome-like nanoparticles from ginger rhizomes inhibited NLRP3 inflammasome activation Mol. Pharm. (2019) D. Fujita et al. Apple-derived nanoparticles modulate expression of...