In this study, we show that ginger exosome-like nanoparticles (GELNs) are selectively taken up by the periodontal pathogen in a GELN phosphatidic acid (PA) dependent manner via interactions with hemin-binding protein 35 (HBP35) on the surface of . Compared with PA (34:2), PA (34:1) ...
Plant-Derived Exosomal MicroRNAs Shape the Gut MicrobiotaIL-22LexAand LGG adherenceginger exosome-like nanoparticlegut microbiota compositionlipid targetingmiRNA/mRNA interactionsmall RNAtryptophan metabolitesSupplementary Figures and Supplementary Tablesdoi:10.1016/j.chom.2018.10.001Teng, Yun...
Plant-derived exosomal microRNAs shape the gut microbiota. Cell Host Microbe. 2018;24(5):637-652.e8. Article CAS PubMed PubMed Central Google Scholar Huang H, Yi X, Wei Q, Li M, Cai X, Lv Y, Weng L, Mao Y, Fan W, Zhao M, Weng Z, Zhao Q, Zhao K, Cao M, Chen J, Cao...
Plant-derived exosomal microRNAs inhibit lung inflammation induced by exosomes SARS-CoV-2 Nsp12. Mol. Ther. 29, 2424–2440 (2021). Article CAS PubMed PubMed Central Google Scholar Tang, Z. et al. Aptamer-conjugated and doxorubicin-loaded grapefruit-derived nanovectors for targeted therapy ...
Symbiotic microbial communities are crucial for human health, and dysbiosis is associated with various diseases. Plant-derived nanovesicles (PDNVs) have a lipid bilayer structure and contain lipids, metabolites, proteins, and RNA. They offer unique advan
The monocyte-derived exosomal CLMAT3 activates the CtBP2-p300-NF-kappaB Transcriptional Complex to Induce Proinflammatory cytokines in ALI. Mol Ther Nucleic Acids. 2020;21:1100–10. Article CAS PubMed PubMed Central Google Scholar Chen Z, Dong WH, Chen Q, Li QG, Qiu ZM. Downregulation of...
The accumulation of amyloid-β protein (Aβ) in brain is linked to the early pathogenesis of Alzheimer’s disease (AD). We previously reported that neuron-derived exosomes promote Aβ clearance in the brains of amyloid precursor protein transgenic mice a
Plant derived components or phytomedicines such as alkaloids and flavonoids have been used from the ancient times against NDDS. They have been potentially proved as the most effective management and therapeutic agents to minimize the crucial aspects of NDDs such as AD, PD, stroke and schizophrenia ...
Plant-derived nanovesicles (PDNVs) have been proposed as a major mechanism for the inter-kingdom interaction and communication, but the effector components enclosed in the vesicles and the mechanisms involved are largely unknown. The plant Artemisia annu
Plant-derived exosomal nanoparticles: potential therapeutic for inflammatory bowel disease Nanoscale Adv. (2023) X. Chen et al. Exosome-like nanoparticles from ginger rhizomes inhibited NLRP3 inflammasome activation Mol. Pharm. (2019) D. Fujita et al. Apple-derived nanoparticles modulate expression of...