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PD-L1表达调控与肿瘤免疫治疗的研究进展 程序性细胞死亡蛋白1(programmed cell death protein 1，PD-1)/程序性死亡配体1(programmed death-ligand 1，PD-L1)是导致肿瘤免疫逃逸的重要免疫检查点分子，阻断PD-1/PD-L1可以重新激活细胞毒性T细胞对肿瘤的杀伤作用，是一种重要的肿瘤免疫治疗方式。肿瘤细胞中PD-L1的...
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近日,苏州大学附属第一医院呼吸与危重症医学科黄建安和刘泽毅教授团队在Cell Death & Differentiation(IF=10.7)杂志上发表题为:KPNB1-mediated nuclear translocation of PD-L1 promotes non-small cell lung cancer cell proliferation via the Gas6/MerTK signaling pathway 的最新研究论文。