PD-L1 expression in osteosarcoma was examined in two patient cohorts using immunohistochemistry (IHC) (n=48, n=59) and expression was validated using quantitative real time PCR (n=21) and western blotting (n=9). IHC was used to determine the presence of tumor infiltrating lymphocytes and ...
非小细胞肺癌肿瘤细胞中 PD-L1 表达对病理学家的挑战-概述 The Challenge to the Pathologist of PD-L1 Expression in Tumor Cells of Non-Small-Cell Lung Cancer-An Overview 上下滑动查看 近年来,应用抗程序性死亡蛋白 1 ...
13. Shirasawa M, Yoshida T, Imabayashi T, et al. Baseline PD-L1 expression and tumour-infiltrated lymphocyte status predict the efficacy of durvalumab consolidation therapy after chemoradiotherapy in unresectable locally advanced...
题为”PD-L1 expression on circulating tumor cells can be a predictive biomarker to PD-1 inhibitors combined with radiotherapy and antiangiogenic therapy in advanced hepatocellular carcinoma”(循环肿瘤细胞上PD-L1的表达可作为PD-1抑制剂联合放射治疗和抗血管生成治疗晚期肝细胞癌的预测生物标志物),旨在确定程...
Janning M, Kobus F, Babayan A, et al. Determination of PD-L1 Expression in Circulating Tumor Cells of NSCLC Patients and Correlation with Response to PD-1/PD-L1 Inhibitors [J] Cancers, 2019, 11, 835. Klaus Pantel 被国际同行称为“液体活检之父”,是该领域的主要...
■研究题目:Prognostic relevance of PD-L1 expression on circulating tumor cells in metastatic breast cancer patients treated with anti-PD-1 immunotherapy ■海报编号:P5-02-12 ■公布时间:12月08日5:00 pm-6:15 pm CT 研究背景:循环肿瘤细胞(CTCs)的检测越来越有前途,因为它是一种微创、可重复、经济有...
Preclinical studies demonstrated that radiation up-regulates PD-L1 expression in tumor cells, providing a rationale for combining PD-1/PD-L1 inhibitors with radiation. However this has not been validated in patients with non-small cell lung cancer due to the difficulty to obtain serial biopsies. ...
Programmed death-1 ligand-1 (PD-L1) an important cancer biomarker that can suppress the immune system and its high expression is often reported to be related with increased tumor aggressiveness in some cancers. Here, we examined and evaluated PD-L1 expression in patients with malignant salivary ...
近日,江南大学附属医院肿瘤研究所黄朝晖团队联合复旦大学附属肿瘤医院黄胜林课题组,在国际知名学术期刊 Advanced Science 杂志发表了题为“Colorectal cancer-derived small extracellular vesicles promote tumor immune evasion by upregulating PD-L1 expression in tumor-associated macrophages”的论文,阐明了结直肠癌来源的细...
Classification of Tumor Immune Microenvironment (TIME) According to PD-L1Expression and Immune Infiltration Predicts Response to Immunotherapy plusChemotherapy in Advanced NSCLC Patients 研究背景: 近年来,基于程序性细胞死亡蛋白-1(PD-1)或程序性死亡配体1(PD-L1)的免疫治疗使肿瘤的治疗策略发生了革命性的变化...