Objectives: Expression of programmed cell death-ligand 1 (PD-L1) has been associated with clinical outcome of programmed cell death-1 (PD-1) pathway blockade in non-small cell lung cancer (NSCLC). The PD-Ll IHC 22C3 pharmDx assay, the only companion diagnostic for pembrolizumab therapy, has...
High PD-L1 expression has been observed in various solid tumours, and a previous study demonstrated that the expression of PD-L1 contributes to poor prognosis65. Although heavily investigated; it remains controversial for the prognostic value of PD-L1 expression in lung cancer, reflecting the incons...
Nikolic Nikola , et al., Brief Report: Predictive value of PD-L1 expression in non-small-cell lung can- cer - should we set the bar higher for monotherapy?, Clinical Lung Cancer (2023)
Nikolic Nikola , et al., Brief Report: Predictive value of PD-L1 expression in non-small-cell lung can- cer - should we set the bar higher for monotherapy?, Clinical Lung Cancer (2023)
PD-L1表达是目前研究最多且证据较充分的疗效预测标志物。最近发表在Cells杂志(IF=4.366)的一篇综述“Tumour PD-L1 Expression in Small-Cell Lung Cancer: A SystematicReview and Meta-Analysis”首次对SCLC中PD-L1的表达进行了全面的荟萃分析。 研...
欢迎关注癌度,我们陪您走好防癌抗癌的每一步! . 参考文献: Nikolic Nikola , et al., Brief Report: Predictive value of PD-L1 expression in non-small-cell lung can- cer - should we set the bar higher for monotherapy?, Clinical Lung Cancer (2023)...
4.PD-1/PD-L1 expression in non-small-cell lung cancer and its correlation with EGFR/KRAS mutations. Cancer Biol THER.2016 Mar online.。 5.Han J J, Kim D W, Koh J, et al. Change in PD-L1 Expression After Acquiring Resistance to Gefitinib in EGFR-Mutant Non-Small-Cell Lung Cancer....
癌度与吉因加启动的“基因检测人人可及”公益计划,最低3000元检测肿瘤用药,您可以联系癌度咨询。 参考文献: Vamsidhar Velcheti, et al., Five-Year Real-World Outcomes With Frontline Pembrolizumab Monotherapy in PD-L1 Expression ≥50% Advanced NSCLC, Clinical Lung Cancer (2024)....
Dietel M, et al. Real-world prevalence of programmed death ligand 1 expression in locally advanced or metastatic non-small-cell lung cancer: The global, multicenter EXPRESS study. Lung Cancer. 2019 Aug; 134: 174-179
www.nature.com/scientificreports OPEN PD-L1 expression in lung adenosquamous carcinomas compared with the more common received: 31 August 2016 accepted: 10 March 2017 Published: 07 April 2017 variants of non-small cell lung cancer Xiaohua Shi*, Shafei Wu*, Jian Sun,Yuanyuan Liu, ...