However, we observed significant toxicity to mice associated with the most effective in vivo selection regimens particularly in animals starting out with the lowest percent of GFP-MGMT* transgenic cells, suggesting that higher starting levels of primary engraftment of GFP-MGMT* cells serves to protect...
Tumor-specific and proliferation-specific gene expression typifies murine transgenic B cell lymphomagenesis J. Biol. Chem., 282 (2007), pp. 4803-4811 View PDFView articleView in ScopusGoogle Scholar 52 A. Sánchez-Aguilera, M. Sánchez-Beato, J.F. García, I. Prieto, M. Pollan, M.A. P...
Phosphodiesterase-5 inhibitor sildenafil prevents neuroinflammation, lowers beta-amyloid levels and improves cognitive performance in APP/PS1 transgenic mice Memory deficit is a marker of Alzheimer's disease (AD) that has been highly associated with the dysfunction of cyclic GMP (cGMP) signaling and an...
Mice, TransgenicMicroscopy, Electron, ScanningSOXB1 Transcription FactorsNeural Stem CellsHearing impairment or vestibular dysfunction in humans often results from a permanent loss of critical cell types in the sensory regions of the inner ear, including hair cells, supporting cells, or cochleovestibular...
Two 3' sequences direct adult erythroid-specific expression of human beta-globin genes in transgenic mice Previous experiments have demonstrated that the human β -globin gene is correctly regulated in transgenic mice. The β -globin gene is not expressed in yo... RR Behringer,RE Hammer,RL ...