that of the plateau phase (6-12 h) and reached the extreme value(P<0.01).It was indicated that the orexins A was involved in the regulation of reproductive function by regulating the energy metabolism , growth and development of sheep throughout the signaling pathway of P-AMPK and P-ERK....
Mihaylova MM, Shaw RJ (2011) The AMPK signalling pathway coordinates cell growth, autophagy and metabolism. Nat. Cell Biol. 13(9), 1016–23. Steinberg GR, Kemp BE (2009) AMPK in Health and Disease. Physiol. Rev. 89(3), 1025–78. Zhang BB, Zhou G, Li C (2009) AMPK: an emerging...
higher than that of the plateau phase (6-12 h) and reached the extreme value(P<0.01).It was indicated that the orexins A was involved in the regulation of reproductive function by regulating the energy metabolism , growth and development of sheep throughout the signaling pathway of P-AMPK ...
Irisin promotes the browning of white adipocytes tissue by AMPKα1 signaling pathway Irisinp-AMPKα1PGC-1αPRDM16UCP12022 Elsevier LtdThe development of white adipose tissue (WAT) browning helps to protect animals from cold conditions and... X Luo,J Li,H Zhang,... - 《Research in Veterinar...
Hence, we provide a unique bioactive compound that inhibits pAmpkα disposal. Together, these results define a new pathway regulating Ampk biological activity and demonstrate the potential utility of modulating this pathway for therapeutic benefit....
p27 cell-cycle inhibitor p27Kip1 p27CT carboxy-terminus of p27 p27NT amino-terminus of p27 PPP pentose phosphate pathway S6 ribosomal protein S6 TSC tuberous sclerosis complex Keywords Tuberous sclerosis complex Rapamycin AMPK mTOR p27 Cell survival ...
关键词: 腺苷酸活化蛋白激酶(AMPK);能量代谢;骨代谢;骨质疏松症The regulatory role of AMPK signaling pathway in bone metabolismWANG Yugang, FAN Qiming, TANG TingtingShanghai Key Laboratory of Orthopedic Implants, Department of Orthopedic Surgery, Shanghai Ninth People’s Hospital, School ofMedicine, ...
4 Effect of p-synephrine on AMPK-FoxO1 signaling pathway and the activities of gluconeogenic enzymes in HepG2 cells 2.4 AMPK信号通路在p-辛弗林抑制肝细胞葡萄糖生成 中的作用 AMPK信号通路中的AMPK是肝脏糖异生的关键因子.本 研究利用AMPK信号通路抑制剂Compound C进一步考察AMPK 信号通路在p-辛弗林抑制肝...
mediate hepatic gluconeogenesis and improve IR via activating AMPK signaling pathway in T2DM mice. Reference: SONG M X, TAN D H, LI B, et al. Gypenoside ameliorates insulin resistance and hyperglycemia via the AMPK-mediated signaling pathways in the liver of type 2 diabetes mellitus mice[J]....
腺苷酸活化蛋白激酶(AMP-activatedproteinkinase,AMPK)是丝,苏氨酸蛋白激酶,一种重要的蛋白激酶,主要协调代谢和能量的需要。 短期效应能调节能量代谢,长期效应能调节基因转录。 激活AMPK,一方面关闭消耗ATP的合成代谢途径;另一方面启动产生ATP的分解代谢途径,故被称为“细胞能量调节器”。能够调节机体的能量代谢,维持能量...