Organ-on-a-chipVirus? 2023 Elsevier B.V.Infectious diseases are caused by the invasion of pathogens into a host. To explore the mechanisms of pathogen infections and cellular responses, human models that can accurately recapitulate human pathophysiology are needed. Organ-on-a-chip is a type of...
Learn more about Lung-on-a-chip Multi-organ-on-a-chip Multi-organ models give detailed information on organ-to-organ crosstalk, pharmacokinetics, and biodistribution. They allow drug effects on the targeted organ, as well as off-target effects on other organs, to be tested. ...
organ‐on‐a‐chipIn article number 1801363 Shiladitya Sengupta, Ali Khademhosseini and co‐workers show organ‐on‐a‐chip systems can provide high‐throughput platforms for drug development, which could potentially bridge the gap between 2D cell culture and animal models. With recent breakthroughs ...
Our Immunocompetent Organ-on-Chip Models Select a model to learn more: Liver-on-Chip Intestine-on-Chip Lung-on-Chip Vasculature-on-Chip Spheroid-on-Chip Development PipelineOur Products & Services Build your own organ models Create in vitro human disease and infection models with our Dynamic...
Organs-on-a-chip models for biological research. Cell 184, 4597–4611 (2021). Google Scholar Pasca, S. P. et al. A nomenclature consensus for nervous system organoids and assembloids. Nature 609, 907–910 (2022). Google Scholar Sato, T. et al. Single Lgr5 stem cells build crypt-...
Find out more about the organ-on-a-chip models, their advantages and future developments in our Topic of the Month.
Three-dimensional models for studying development and disease: moving on from organisms to organs-on-a-chip and organoids. Integr. Biol. 8, 672–683 (2016). Google Scholar Sin, A., Baxter, G. & Shuler, M. Animal on a Chip: A Microscale Cell Culture Analog Device for Evaluating ...
[4]https://cn-bio.com/of-mice-and-men-will-human-organ-on-a-chip-disease-models-replace-animal-use/ [5]https://cn-bio.com/resource/ebr-a-pressing-need-for-accurate-preclinical-models-of-metabolic-disease/ [6]https://www.nature.com/articles/s42255-020-0214-9 ...
Using a novel "organ-on-a-chip" model, Baker Heart & Diabetes Institute researchers have discovered a potential therapeutic target that may slow down vascular aging and reduce heart disease, kidney dysfunction and vascular dementia.
Learn more about Lung-on-a-chip Multi-organ-on-a-chip Multi-organ models give detailed information on organ-to-organ crosstalk, pharmacokinetics, and biodistribution. They allow drug effects on the targeted organ, as well as off-target effects on other organs, to be tested. ...