RNA is the genetic material converting the genetic code that it gets from DNA into protein. While less than 2 % of RNA is converted into protein , more than 98 % of it can not be converted into protein and named as non-coding RNAs. 70 % of noncoding RNAs consists of introns , ...
常见非编码RNA介绍 非编码RNA(non-coding RNA,ncRNA),指的是不被翻译成蛋白质的一类RNA,转录ncRNA的DNA序列叫非编码RNA基因。随着生物学的发展和多学科的相互渗透,人们对ncRNA的认识日渐加深,近十几年来… 大名不知道发表于小小芦聊科... 编码RNA与非编码RNA(一) lcy19...发表于生化杂谈打开...
ncRNA为蛋白质编码的RNA分子,而是在细胞内执行其他功能。ncRNA基因有许多类型,其中一些包括: 转移RNA(tRNA):tRNA负责在蛋白质合成过程中将氨基酸带到核糖体上。有20种不同的tRNA基因,每种基因都编码一种特定的氨基酸。 核糖体RNA(rRNA):rRNA是核糖体的主要组成部分,是负责合成蛋白质的细胞机器。有几种不同类型的rR...
The functions of most long non-coding RNAs (lncRNAs) are unknown. In contrast to proteins, lncRNAs with similar functions often lack linear sequence homology; thus, the identification of function in one lncRNA rarely informs the identification of function in others. We developed a sequence comparis...
non-coding rna名词解释non-coding rna名词解释 非编码RNA(non-coding RNA,ncRNA)指的是在转录成RNA时不被翻译成蛋白质的RNA分子。与编码蛋白质的mRNA相比,ncRNA的功能非常多样,包括调控基因表达、RNA的剪接和稳定性、染色体转录后修饰等。非编码RNA是生物学研究领域中的一个热门话题,对于揭示细胞及多细胞生命现象的...
非编码RNA(Non-coding RNA)是指不编码蛋白质的RNA,包括miRNA、lncRNA、circRNA、piRNA等。非编码RNA发挥功能的方式很多,可以与蛋白、DNA和RNA相互作用,参与多种细胞活动,主要包括基因的激活和沉默,RNA的剪接、修饰和编辑,蛋白质的翻译等。 1.miRNA:miRNA是一类由内源基因编码的长度约为22个核苷酸的非编码单链RNA分...
non-codingRNA(20-20000nt)RNAmRNA smallnon-codingRNA(sncRNA)(20-500nt)longnon-codingRNA(lncRNA)(>500-20000nt)Non-codingRNA:Versatilityinformandfunction NoncodingRNAgenesaresurprisinglynumerous.NoncodingRNAhaveaverydifferentfunctions.TimeforRNomics Cell,89:669–672,May30,1997 PNAS,97(26):14035-14037...
Long non-coding RNA (lncRNA) has diverse functions. Here the authors show that a lncRNA, NORAD, interacts with an immune transcription factor, STAT3, to facilitate STAT3 nuclear import and thereby modulating the intranuclear balance between STAT3 and STAT1 and the downstream activation of anti-vir...
非编码RNA (non-coding RNA,ncRNA)指不翻译成多肽的RNA。按照长度不同,短于200nt的归为小非编码RNA (small non-coding RNAs,sncRNAs),长于200nt的归为长非编码RNA (long non-coding RNAs,lncRNAs)。 非编码RNA参与的复杂多变的调控过程对于血脂代谢和动脉粥样硬化的发生发展更为重要。
Non-coding RNAs are a big class of RNAs, which were discovered in the last one decade. However, it plays steamily important roles in both plants and animals. The following hot topics will be covered by this special issue...