The treatment of patients with glioblastoma is a showcase for improved technology in many disciplines of medicine. Imaging technology has improved substantially, leading to more accurate and rapid diagnosis; better anatomic localization, which leads to improvements in neurosurgical results; and earlier ...
The purpose of this review is to summarize the current knowledge of molecular mechanisms of GBM and highlight the novel strategies and concepts for the treatment of GBM. 展开 关键词: CRISPR/Cas9 genome editing gene therapy glioblastoma immunotherapy molecular mechanisms DOI: 10.18632/oncotarget....
The brain cancer glioblastoma (GBM) is characterized by the presence of cells that can mimic human neurons, even growing axons and making active connections with healthy brain neurons. This cancer almost always recurs after initial treatment, and recurrent tumors are always resistant to therapy. ...
The article focuses on a study which examined the treatment patterns and survival of patients with glioblastoma who received treatment in a U.S. community setting. Results of the study showed that most of these patients underwent adjuvant temozolomide therapy and radiotherapy. The study found that ...
Nanoparticle-Delivered Antisense MicroRNA-21 Enhances the Effects of Temozolomide on Glioblastoma Cells Glioblastoma (GBM) generally exhibits high IC50 values for its standard drug treatment, temozolomide (TMZ). MicroRNA-21 (miR-21) is an oncomiR overexpresse... JS Ananta,R Paulmurugan,TF Massoud ...
What is glioblastoma?(CBS News, 07/19/17) Cancer expert says McCain's treatment option is "tolerable"("CBS This Morning," 07/20/17) It may explain why the senator seemed somewhat disoriented last month while questioning former FBI director James Comey. ...
Glioblastoma (GBM) is a fast growing and aggressive brain cancer that has a high mortality rate. Median survival is 16 months, with only around 5% of patients surviving more than five years. Surgery and radiation therapy are important for the treatment of GBM, and chemotherapy is helpful in ...
Glioblastoma (GBM) is the most frequent and malignant brain tumor with an overall survival of only 14.6months. Although these tumors are treated with surgery, radiation and chemotherapy, recurrence is inevitable. A critical population of tumor cells in terms of therapy, the so-called cancer stem ...
We grow the modified CAR T cells for a few days in the lab, freeze them in batches, test them for cancer killing ability, then give them back to the patient through an IV drip. Who can join the trial? This is the first time we've tested this treatment in patients, so our first ...
Novel Treatment Approaches in Glioblastoma : Episode 8 Video December 20, 2016 New Long-term Data for Tumor-Treating Fields in GlioblastomaTranscript:Daniela Bota, MD: At the Society for Neuro-Oncology Meeting this year, we have a new report on the long-term data for the EF-14 study. And ...