New insights for precision treatment of glioblastoma from analysis of single-cell lncRNA expressionLncRNASingle-cell RNA-seqPrecision medicineCancer classificationGlioblastomaIntroductionMeng, QingkangZhang, YanLi, GuoqiLi, YunongXie, HongboChen, Xiujie...
Targeted alpha therapy (TAT) is emerging as a potential additional treatment for glioblastoma (GB), a disease which has confounded oncologists for decades due to its aggressive nature and strong resistance to existing therapies. The current standard treatment for GB is surgery, followed by external...
The brain cancer glioblastoma (GBM) is characterized by the presence of cells that can mimic human neurons, even growing axons and making active connections with healthy brain neurons. This cancer almost always recurs after initial treatment, and recurrent tumors are always resistant to therapy....
We also discuss the possibility of targeting p53-mediated ferroptotic responses for the treatment of human cancers and potentially, other diseases.This is a preview of subscription content, access via your institution Access optionsSubscribe to this journal Receive 12 print issues and online access ...
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patient populations, eventually leading to personalized treatment approaches. For example, the GBM-AGILE is a novel multi-arm platform trial designed to evaluate a therapy based on biomarker status, including the EGFR alteration and the MGMT promoter methylation status, among patients with glioblastoma....
22 February 2024 Catherine Eckford / European Pharmaceutical Review The innovative treatment significantly increased survival in patients with malignant pleural mesothelioma, a rare, aggressive cancer, according to Phase III data from UK researchers. ...
The purpose of this work is to investigate theoretically how glioblastoma multiforme (GBM) can be effectively treated by combining the fast hyperthermia generated by this focused ultrasound device with external beam radiotherapy. To investigate the effect of tumor growth, we have developed a ...
123,124 Intracranial tumours, such as glioblastomas7 and pituitary neuroendocrine tumours (PitNETs),125 were found to contain intratumoural microorganisms, and the abundance of microorganisms in different subtypes of the PitNETs was also different, which Fusobacteriaceae, Tissierellaceae, and Aerococc...
(pcALCL) and mycosis fungoides who had been previously treated. Approval for the use of BV was based on the phase III ALCANZA trial, which showed a significant increase in an objective response lasting at least 4 months after BV treatment compared to the objective response to a physician’s ...