New insights for precision treatment of glioblastoma from analysis of single-cell lncRNA expressionLncRNASingle-cell RNA-seqPrecision medicineCancer classificationGlioblastomaIntroductionMeng, QingkangZhang, YanLi, GuoqiLi, YunongXie, HongboChen, Xiujie...
The brain cancer glioblastoma (GBM) is characterized by the presence of cells that can mimic human neurons, even growing axons and making active connections with healthy brain neurons. This cancer almost always recurs after initial treatment, and recurrent tumors are always resistant to therapy....
Malignant tumors are one of the major causes of death worldwide, and the development of better treatments is urgently needed. There are many types of cancer treatment, such as surgery, chemotherapy, radiation therapy, immunotherapy, and targeted therapy,
We also discuss the possibility of targeting p53-mediated ferroptotic responses for the treatment of human cancers and potentially, other diseases.This is a preview of subscription content, access via your institution Access optionsSubscribe to this journal Receive 12 print issues and online access ...
Glioblastoma is the most ... L Gamarra,AC Silva,TR Oliveira,... - 《International Journal of Nanomedicine》 被引量: 235发表: 2011年 Hyperthermia (42 degrees C) as an adjuvant to radiotherapy and chemotherapy in the treatment of the allogeneic VX2 carcinoma in the rabbit. The BJC is owned...
Ongoing studies are investigating ADI-PEG20 in patients with cancers such as sarcoma or glioblastoma multiforme, which are dependent on arginine. Following the positive data from the Phase III trial, this innovative chemotherapy could benefit other types of cancer, the researchers concluded. ...
- All-time highest 24-hour precipitation: 15.1 inches (Hokah Wastewater Treatment Plant on Aug. 19, 2007) - All-time highest 24-hour snowfall: 36 inches (Wolf Ridge Environmental Learning Center on Jan.7, 1994) Hokah, a city in Houston County, had the state's heaviest one-day rainfall ...
(BLENREP®, GlaxoSmithKline) is a first-in-class anti-BCMA ADC that was granted accelerated approval by the FDA in August 2020 as a monotherapy treatment for adult patients with RRMM who had received at least four prior therapies; belantamab mafodotin includes an anti-CD38 mAb, the ...
Mutations in IDH1 and IDH2 occur in about 20% of AML patients and are common in other malignancies, such as glioblastoma.47 These mutant enzymes have become promising targets for new therapies, as they promote tumorigenesis in cells through production of the oncometabolite, 2-hydroxyglutarate (2-...
Furthermore, mRNA therapy had demonstrated various results in different cancer types, including melanoma, glioblastoma, acute myeloid leukemia (AML), and renal cell carcinoma [11], indicating that additional complexity remains to be explored. For cancer vaccination, even if an antigen can induce ...