Brenden, New York City When my mother-in-law fell ill, my husband and I were scrambling to sort out how to best go forward. We had a ton of questions - Medicaid? How does it work with Medicare? Is it possible to get in-home care? What other resources are out there for her? What...
Brenden, New York City When my mother-in-law fell ill, my husband and I were scrambling to sort out how to best go forward. We had a ton of questions - Medicaid? How does it work with Medicare? Is it possible to get in-home care? What other resources are out there for her? What...
The antitumoral drug Temozolomide (TMZ) constitutes, in combination with radiotherapy, the current standard of care for glioblastoma (Stupp et al., 2005). However, the action of TMZ may be counteracted in tumors by the expression of the DNA repair enzyme MGMT, which repairs TMZ-induced DNA ...
they can also drive tumor growth. Most notably, the role of the androgen receptor (AR) in prostate cancer has been extensively studied. Recent data suggest that AR signaling may also be important in breast cancer, glioblastoma, and additional tumor types with AR expression...
time consuming treatment calls for expensive gear and a high standard of skill. Electroporation of zygotes offers a simplified and much more streamlined method to transfect mammalian zygotes. There are a number of studies examining the parameters used in electroporation of mouse and rat zygotes. ...
there was large variability in the bony anatomy and soft tissueDMARDs (biologic)envelope for the knee so flexion imbalance may possibly occur. A patient-specific alignment navigated balanced TKA technique was carried out wherein the tibia is slashed anatomically as much as 3° of varus, then a...
Last week, I noticed fenbendazole being "repurposed" to treat cancer. Now it's ivermectin. Truly these two drugs are the new laetrile.
for immunotherapy. This holds promise for glioblastomas (GBMs), the most common primary tumors of this adult mindMavoglurant price, that are resistant to standard-of-care therapy. Although most clinical studies enlist patients at recurrence, many preclinical scientific studies have-been completed ...
Because mutational processes differ across human populations34, there is potential for this to confound analyses of the somatic mutation spectrum. Given the high number of residual germline variants post-filtering (Fig.1b), even slight differences in the germline spectrum can cause large deviations in...
One of major concerns for brain tumor drug treatment is the penetration of blood–brain barrier (BBB). A previous study has shown the effects of RG7388 treatment in glioblastoma orthotopic models [30]. However, the BBB in the brainstem area is generally regarded as more intact for DIPG as ...