2043#Background:Patients with glioblastoma (GBM) face three major challenges. First, the tumor itself as well as chemoradiation treatment result in lymphopenia, which is associated with shorter survival. Second, the tumor microenvironment (TME) has a paucity of T cells and consequently, ...
This review seeks to highlight the latest strides in targeted glioblastoma therapy by focusing on the application of inorganic smart nanoparticles. Beyond exploring the general role of nanotechnology in medical applications, this review delves into groundbreaking strategies for glioblastoma treatment, show...
The brain cancer glioblastoma (GBM) is characterized by the presence of cells that can mimic human neurons, even growing axons and making active connections with healthy brain neurons. This cancer almost always recurs after initial treatment, and recurrent tumors are always resistant to therapy....
Fast Facts: Glioblastoma: New molecular concepts pave the way for advances in diagnosis and treatment 来自 ResearchGate 喜欢 0 阅读量: 11 作者:M Mcnamara,S Brandner,SC Thust 出版时间: 2020/02/26 ISBN: 978-1-912776-70-2 收藏 引用 批量引用 报错 分享 ...
Neoangiogenesis is a critical feature of glioblastoma, and several VEGFR-targeting small molecules have been extensively investigated for the treatment of glioblastoma [26]. However, exploration of multitarget TKIs such as cediranib and pazopanib as monotherapy have failed to improve the survival of ...
Biomedicine & Pharmacotherapy Volume 157, January 2023, 114084New light on treatment of cervical cancer: Chinese medicine monomers can be effective for cervical cancer by inhibiting the PI3K/Akt signaling pathway Author links open overlay panelFangyuan Liu a 1, Jiayue Xu b 1, Rui Yang a, Shao...
(pcALCL) and mycosis fungoides who had been previously treated. Approval for the use of BV was based on the phase III ALCANZA trial, which showed a significant increase in an objective response lasting at least 4 months after BV treatment compared to the objective response to a physician’s ...
LanguageBrain Disorders: Affecting Brain Function, Structure and NeurochemistryBrain Plasticity, Cognitive Training and Mental States AssessmentBrain-Computer Interfaces for Human AugmentationBrain-Computer Interfaces: Current Trends and Novel ApplicationsCerebral Etiology and Treatment of the Gilles de la ...
Tumor recurrence is the main challenge in glioblastoma (GBM) treatment. Gold standard therapy temozolomide (TMZ) is known to induce upregulation of IL8/CXCL2/CXCR2 signaling that promotes tumor progression and angiogenesis. Our aim was to verify the alterations on this signaling pathway in human ...
Methylprednisolone substituted lipid nanoparticles deliver C3 transferase mRNA for combined treatment of spinal cord injury Haoru Dong Zongxing He Rong Xie Journal of Nanobiotechnology (2025) Tuberculosis vaccines and therapeutic drug: challenges and future directions Yajing An Ruizi Ni Wenping Gong ...