monoclonal gammopathy of undetermined significance (MGUS)smoldering multiple myeloma (SMM)Monoclonal gammopathy of undetermined significance (MGUS) accounted for 56% of the 1026 patients with a monoclonal plasma cell disorder seen at the Mayo Clinic during 1992. Approximately 3% of persons older than 70...
The prevalence of monoclonal gammopathy of undetermined significance (MGUS), a premalignant plasma-cell disorder, among persons 50 years of age or older ha... RA Kyle,TM Therneau,SV Rajkumar,... - 《New England Journal of Medicine》 被引量: 1243发表: 2006年 Global gene expression profiling ...
BACKGROUND: Approximately 25% of patients with monoclonal gammopathy of undetermined significance (MGUS) eventually develop multiple myeloma (MM) or a related plasma cell disorder that is universally fatal. In this report, we examine the changes that occur in the clonal plasma cell that are likely...
A diagnosis of CIDP with underlying plasma cell disorder was made after serum electrophoresis, immune-fixation and electrodiagnostic studies. The patient was started on prednisone 60 mg once daily, discharged and advised for monthly follow-up. Diagnosis of CIDP and the underlying cause is ...
Introduction Monoclonal gammopathy of undetermined significance (MGUS) is a clinically asymptomatic premalignant plasma cell disorder. Previous studies in Western countries have described the prevalence of MGUS in Caucasians. However, data is limited in Chinese population. We therefore performed this study ...
Plasma cell disorders are not uncommonly reported in young patients with HIV infection. These disorders range from benign polyclonal hypergammaglobulinemia... BJ Dezube,DM Aboulafia,L Pantanowitz - 《Aids Reader》 被引量: 65发表: 2004年 Monoclonal gammopathy associated with HIV infection. In this...
monoclonal gammopathypathogenesisskinCutaneous manifestations of monoclonal gammopathy can precede, be concurrent with, or follow the onset of the plasma cell disorder. These manifestations may be classified as specific, resulting from direct infiltration of the skin by malignant plasma cells, or ...
Pure red cell aplasia (PRCA) is a rare disorder characterized by inhibition of erythroid precursors in the bone marrow and normochromic, normocytic anaemia with reticulocytopenia. Among 51 PRCA patients, we identified 12 (24%) patients having monoclonal gammopathy, monoclonal gammopathy of undetermin...
These findings highlight the importance of performing the myeloma FISH panel on all bone marrow biopsy samples from patients with plasma cell dyscrasia. If bone marrow evaluation does not reveal a clonal haematological disorder, the next step could be to perform imaging studies (such as CT with...
Previously thought to be best described as a plasma cell disorder, Waldenstr枚m macroglobulinaemia (WM) is now understood to be a distinct clinicobiologica... ML Mcmaster,N Caporaso - 《British Journal of Haematology》 被引量: 41发表: 2010年 IL21R expressing CD14+CD16+ monocytes expand in ...