The two drugs are derived from thesamemonoclonalantibody and hence have similar molecular structure. legco.gov.hk legco.gov.hk 這兩種藥物由同一個單株抗體衍生出來,因此有相若的分子結構。 legco.gov.hk legco.gov.hk It is easy to see how conjugating a large protein (> 100 kd) or a hydrophobic...
The International Kidney and Monoclonal Gammopathy Research Group initiated a collaborative effort aimed at delineating treatment strategies. What is MGRS? The B-cell clone corresponds to the definition of a dangerous small B-cell clone, suggesting that its deleterious consequences are not directly ...
The term monoclonal gammopathy of renal significance (MGRS) comprises a group of diseases pathogenetically characterised by proliferation of a B-cell or plasma cell clone that synthesises and secretes a monoclonal immunoglobulin or its components (light and/or heavy chains), that may deposit and ca...
Multiple myeloma (MM) is a highly heterogenous disease that exists along a continuous disease spectrum starting with premalignant conditions monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM) that inevitably precede MM. Over the past two decades, significant pro...
indicative of the accumulation of epigenetic/genetic changes during the typical development of the disease from monoclonal gammopathy of undetermined significance, through smoldering (asymptomatic) myeloma, to symptomatic MM.4 Clinically, symptomatic MM is characterized by end-organ damage, generally involving...
Define monoclonal antibody. monoclonal antibody synonyms, monoclonal antibody pronunciation, monoclonal antibody translation, English dictionary definition of monoclonal antibody. n. Any of the highly specific antibodies produced in large quantity by the
monocytosis[内科] 单核细胞增多(症) monoclonal英英释义 adjective produced by, being, composed of, or caused by cells derived from a single cellespecially: relating to, being, or caused by a monoclonal antibody or monoclonal antibodies monoclonal assays see also monoclonal gammopathy ...
Before proceeding to treatment selection for multiple myeloma, it is important to exclude monoclonal gammopathy of unknown significance or any similar smou... L Camba,PBGM Durie - 《Drugs》 被引量: 3发表: 1992年 Comparision of the diagnostic sensitivity of biochemical tests in the screening of ...
Successful treatment of IgM-monoclonal gammopathy of undetermined significance associated with cryoglobulinemia and cold agglutinin disease with immunochemotherapy with rituximab, fludarabine, and cyclophosphamidedoi:10.1007/s00277-011-1322-0Joyeeta Bhattacharyya...
In 2012, the IKMG introduced the term monoclonal gammopathy of renal significance (MGRS) to describe haematological conditions that produce a monoclonal immunoglobulin associated with kidney injury33. Since then, the IKMG has published recommendations for the treatment of MGRS34 and a classification ...