Monoclonal gammopathy of undetermined significance (MGUS) is characterised by the presence of a monoclonal paraprotein in the blood, without the characteristic end organ damage seen in multiple myeloma. MGUS is more common in older age groups and has a risk of progression to myeloma of 1% per ...
Synonyms for monoclonal gammopathy of unclear significance in Free Thesaurus. Antonyms for monoclonal gammopathy of unclear significance. 1 word related to gammopathy: pathology. What are synonyms for monoclonal gammopathy of unclear significance?
What Is the Significance of Monoclonal Gammopathy of Undetermined Significance (MGUS)? Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant plasma celldyscrasia that is to multiple myeloma did not show a significant di... M Kwa - 《Clinicalcorrelations Org》 被引量: 0发表:...
More often, however, it represents a monoclonal gammopathy of undetermined significance (MGUS). How do you know when the problem requires immediate attention, and what do you tell your patient? In this article, Dr Brigden presents criteria for diagnosis of multiple myeloma, smoldering myeloma, ...
139 What is monoclonal B-cell lymphocytosis (MBL)? The presence of a monoclonal B-cell population in numbers < 5000/mL with no other features of a lymphoproliferative disorder. Akin to MGUS (monoclonal gammopathy of undetermined significance) and its relationship with multiple myeloma, CLL...
DIAGNOSISDISEASESTREATSKINMonoclonal proteins can provide important information on the diagnosis of several non-malignant systemic inflammatory disorders. At low concentration, they most commonly represent monoclonal gammopathy of undetermined significance (MGUS), whereas high concentrations often signify plasma ...
What is the appropriate initial management for a patient found to have a monoclonal gammopathy? Evidence-based answer: Initial management of a newly found monoclonal gammopathy (M-protein) includes history, physical examination, and ancillary studies' complete blood count (CBC), serum calcium, serum...
`evolving' MGUS (see the section `Predictors of malignant transformation'), the mechanisms that limit the growth of the emerging plasma cell clone would not exist and, irrespective of the initial plasma cell mass, all these patients would eventually end up with a symptomatic monoclonal gammopathy....
Monoclonal gammopathy and APS are independently associated with an increased thrombotic risk and the observed thrombotic events described might be due to the cumulative effect of the two. However, it is likely that the monoclonal paraprotein has aPL-antibody activity driving the prothrombotic environment...
Keywords: monoclonal gammopathy of undetermined significance; multiple myeloma; T lymphocytes; cytokine; alarmin; inflammation; immunosurveillance 1. Introduction 1.1. General Considerations for MGUS The term monoclonal gammopathy of undetermined significance (MGUS) designates the existence of a serum monoclonal...