Further study for both monoclonal and polyclonal TBMID is required in the future.doi:10.1111/pin.13092Anri SawadaMasayoshi OkumiShigeru HoritaTomomi TamuraAkira ShimizuJohn Wiley & Sons, LtdPathology International
Objectives: To determine the risk factors, the clinical significance, and the evolution of monoclonal gammopathy (MG) and hypergammaglobulinemia (HG) in Gaucher disease (GD). Methods: Patients from the French GD Registry with information... Y Nguyen,J Stirnemann,B Monia,... - 《Molecular Gen...
Monoclonal and polyclonal gammopathy measured by serum free light chain and immunofixation subdivide the clinical outcomes of diffuse large B-cell lymphoma according to molecular classification. Ann Hematol. 2014;93:1867–77. Article CAS PubMed Google Scholar de Leval L, Harris NL. Variability in ...
Spuriously low levels of plasma phosphate have been reported previously in patients with multiple myeloma and polyclonal gammopathy. We report 2 cases of spurious hypophosphatemia in patients with elevated concentrations of serum monoclonal immunoglobulins, 1 of whom had monoclonal gammopathy of undetermined...
摘要: Hypergammaglobulinemia can result from both polyclonal and monoclonal immunoglobulin production. Polyclonal hypergammaglobulinemia is usually associated with inflammatory conditions and detected on serum protein electrophoresis (SPEP) as broad indistinct band. In contrast, monoclonal gammopathy is...
a homogeneous immunoglobulin resulting from the proliferation of a single clone of plasma cells; during electrophoresis of serum, it appears as a narrow band or "spike"; it is characterized by heavy chains of a single class and subclass and by light chains of a single type. ...
Related to Monoclonal antibodies: Polyclonal antibodiesmonoclonal antibody n. Any of the highly specific antibodies produced in large quantity by the clones of a single hybridoma cell. American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcou...
MP8: MONOCLONAL GAMMOPATHY CHARACTERIZATION USING SERUM PROTEIN ELECTROPHORESIS IN A MAJOR URBAN POPULATION Neuropathy was seen in 7 (14%) patients; 71% (5/7) had polyclonal gamma Ig increase, and 1 (14%) case with co-HIV infection had monoclonal IgG... D Laskar,K Shafique,C Lu,... -...
Eight patients manifested with Sjgren's syndrome, one had systemic lupus erythematosus, one presented initially with Raynaud's phenomenon, and two had a monoclonal gammopathy. "Composite lymphomas" were encountered in seven patients. In ... BY Ngan,RA Warnke,M Wilson,... - 《Human Pathology》...
CD56+, and CD19−), although the proportion of phenotypically normal plasma cells is higher in patients with MGUS than in those with overt myeloma.20Thus, there are 2 populations of plasma cells in persons with MGUS: 1 is normal and polyclonal (CD38+, CD56−, CD19+), and the other...