Monoclonal gammopathy of undetermined significance (MGUS) is characterized by increased production of an immunoglobuling (Ig) from a clone of plasma cells and is a pre-malignant disorders in subjects older than 50 years. The prevalence of MGUS in Caucasian population is still not determined. MGUS ...
The concept of monoclonal gammopathy of undetermined significance (MGUS) was first introduced in 1978 by Robert Kyle1. This premalignant condition is characterized by the presence of a serum monoclonal immunoglobulin <30 g/l and <10% monoclonal bone marrow plasma cells in a patient who does not...
Monoclonal gammopathy of undetermined significance (MGUS) MGUS is characterized by a serum M-protein concentration of less than 30 milligrams (3 g/dl), fewer than 10% plasma cells in the bone marrow, no or only sm... RA Kyle - 《Baillières Clinical Haematology》 被引量: 90发表: 1995年...
Cardiac amyloidosis with a coexistent monoclonal gammopathy: A diagnostic challengedoi:10.2143/TVG.69.10.2001393Amyloidosis is a multisystem disease characterized ... H Maes,JV Cleemput,G Verhoef,... - 《Tijdschrift Voor Geneeskunde》 被引量: 0发表: 2013年 IgG kappa monoclonal gammopathy of undetermin...
A monoclonal gammopathy precedes multiple myeloma in most patients. Blood 2009; 113: 5418–5422. 15 Tai YT, Chang BY, Kong SY, Fulciniti M, Yang G, Calle Y et al. Bruton tyrosine kinase inhibition is a novel therapeutic strategy targeting tumor in the bone marrow microenvironment in ...
Schnitzler syndrome (SS) is a rare autoinflammatory disorder characterized by a recurrent urticarial rash and a monoclonal immunoglobulin M gammopathy, as well as 2 of the following minor criteria: recurrent fever (>38°C), objective signs of abnormal bone remodeling, elevated C-reactive protein lev...
Castleman's disease is a rare lymphoid neoplasm that is characterized by the proliferation of lymphoid tissue. A case of young woman having the plasma cell... Y Oida,K Shimizu,M Mukai,... - 《Clinical Imaging》 被引量: 37发表: 2008年 Intensity modulated radiation therapy (IMRT) for the ...
Idiopathic monoclonal (IgA) gammopathy in a dog was differentiated from multiple myeloma, based on the lack of Bence Jones proteinuria, no osteolysis, and no plasma cell infiltration into bone marrow, as well as on the stability of the gammopathy for over 18 months. The dog was not treated ...
CANOMAD (chronic ataxic neuropathy, ophthalmoplegia, immunoglobulin M [IgM] paraprotein, cold agglutinins, and disialosyl antibodies) is a rare syndrome characterized by chronic neuropathy with sensory ataxia, ocular, and/or bulbar motor weakness in the presence of a monoclonal IgM reacting against...
is characterized by the proliferation of clonal plasma cells without B cells and by the absence ofMYD88mutation. The t(11;14)IGH::CCND1or other myeloma-associatedIGHrearrangements may be present. Conversely, IgM MGUS, NOS is characterized by a proliferation of monoclonal B cells (without lympho...