Quality of lifeFatigueDepressionPolyneuropathy associated with monoclonal gammopathy of undetermined significance (MGUS-PNP) has a chronic and slowly progressive course but can lead to significant disability and reduced quality of life (QoL). The aim of this study was to analyze QoL in MGUS-PNP ...
5. Monoclonal Gammopathy of Undetermined Significance (MGUS) This is a condition that can lead to active myeloma. It involves M proteins, which are abnormal antibodies made by myeloma cells. But MGUS doesn't cause other symptoms of myeloma. In people who live with this condition for 20 years,...
Two patients did not have immunoglobulin-derived amyloidosis despite the presence of a monoclonal gammopathy. Eight patients were diagnosed with two types concurrently, and one patient had an 11-year interval between diagnoses. Histopathological distribution of amyloid was variable with vascular, ...
Clonal circulating cells are common in plasma cell proliferative disorders: a comparison of monoclonal gammopathy of undetermined significance, smoldering ... The blood of most patients with active multiple myeloma (MM) contains cells related to the bone marrow tumor. However, identifying clonal cells ...
Certainly, direct infiltration is also seen, but unlike leukemias, lymphomas can produce monoclonal proteins that can injure the kidney, either through deposition—like in monoclonal gammopathy of renal significance—or the monoclonal proteins can activate complement-causing TMA. So, a numbe...
Nonorgan-specific autoantibodies and immunoglobulin allotypes in relatives of patients with monoclonal gammopathy. Polyclonal immunoglobulin increase, rheumatoid factor, antinuclear antibodies and cold lymphocytotoxins were detected 10, 8, 7 and 8 times, respectively, i... P Youinou,C Fauchier,O Prou...
TWO UNUSUAL TYPES OF ANGIOPATHY IN PATIENTS WITH PERIPHERAL NEUROPATHY ASSOCIATED WITH MONOCLONAL IgG GAMMOPATHY: 67.An abstract is unavailable. This article is available as a PDF only.doi:10.1097/00005072-198705000-00074Gherardi, R.Bdrimont, M....
Background: Two patients were admitted to Mie Prefectural General Medical Center and diagnosed as chronic hepatitis C complicated with monoclonal gammopathy of undetermined significance (MGUS). Methods: The MGUS class were immunoglobulin (Ig)G. The hepatitis C virus (HCV) RNA genotype was Ib. Based...
In one sample obtained from a patient with a biclonal gammopathy, the L chains were resolved as 4 different spots. Our results confirm that 2-D PAGE is an excellent tool to study Ig. Analysis of the L chain region of the gels was particularly informative. Several monoclonal L chains ...
In one sample obtained from a patient with a biclonal gammopathy, the L chains were resolved as 4 different spots. Our results confirm that 2-D PAGE is an excellent tool to study Ig. Analysis of the L chain region of the gels was particularly informative. Several monoclonal L chains ...