Multiple myeloma (MM) is a highly heterogenous disease that exists along a continuous disease spectrum starting with premalignant conditions monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM) that inevitably precede MM. Over the past two decades, significant pro...
Successful treatment of IgM-monoclonal gammopathy of undetermined significance associated with cryoglobulinemia and cold agglutinin disease with immunochemotherapy with rituximab, fludarabine, and cyclophosphamidedoi:10.1007/s00277-011-1322-0Joyeeta Bhattacharyya...
Dear Editor, A 69-year-old woman with peripheral coldness as well as pain, numbness of the hands and feet, and purpura on the extremities on exposure to cold stimulation was referred to us. Physical examination found livedo reticularis on the distal extremities (Fig. 1a ), Raynaud's phenomen...
Treatment of monoclonal gammopathy with alkylating agents does not necessarily influence the activity of the skin disease and vice versa. These researchers summarized all reported treatments of NXG of the skin, with or without underlying malignant condition and based on articles from the PubMed data...
The treatment paradigm in myeloma is constantly changing. Upfront use of monoclonal antibodies like daratumumab along with proteasome inhibitors (PI)s, and immune modulators (IMiD)s have significantly improved survival and outcomes, but also cause unique
Blotta, S.et al. Identification of novel antigens with induced immune response in monoclonal gammopathy of undetermined significance.Blood114, 3276–3284 (2009). CASPubMedPubMed CentralGoogle Scholar Bae, J.et al. Identification of novel myeloma-specific XBP1 peptides able to generate cytotoxic T...
Multiple myeloma is one of many conditions that can cause problems with your plasma cells. Others include: Monoclonal gammopathy.This is when your plasma cells make too many copies of one antibody. Multiple myeloma is a form of this disorder. Another form, monoclonal gammopathy of undetermined sig...
The pre-myeloma condition, monoclonal gammopathy of undetermined significance (MGUS), is twice as common in Black people as it is in white people. They only make up 6% of those in myelomaclinical trials. They may not be offered the newest treatment options. ...
Monoclonal gammopathy of unknown significance (MGUS) and smoldering multiple myeloma (SMM) are asymptomatic plasma cell dyscrasias, with a propensity to pr... Neha,Korde,Sigurdur,... - 《Blood》 被引量: 256发表: 2011年 Treatment of plasma cell dyscrasias with lenalidomide. mechanisms of action,...
Intermittent cyclophosphamide and prednisone treatment of polyneuropathy associated with monoclonal gammopathy of undetermined significance. Neurology. 1996;47(5):1227–33. Article CAS Google Scholar Hamidou MA, Belizna C, Wiertlewsky S, Audrain M, Biron C, Grolleau JY, Mussini JM. Intravenous ...