Ginsberg A, Mullinax F: Pernicious anemia and monoclonal gammopathy in a patient with IgA deficiency. Amer J Med 48:787–791, 1970Ginsberg A, Mullinax F. Pernicious anemia and monoclonal gamm- opathy in a patient with IgA deficiency. Am J Med. 1970;48: 787-791....
History and Physical Examination Monoclonal gammopathy of undetermined significance (MGUS) is usually an unexpected finding during an evaluation for an unrelated disorder. The advances in quantification of an M-spike by immunofixation contribute to the increasing number of patients identified as having ...
The term monoclonal gammopathy of undetermined significance (MGUS) denotes the presence of a monoclonal protein (M protein) in persons without evidence of multiple myeloma (MM), Waldenström’s macroglobulinemia (WM), AL amyloidosis (AL), or other related diseases. MGUS is characterized by a seru...
The term monoclonal gammopathy of undetermined significance ( MGUS ) denotes the presence of a monoclonal protein (M protein) in persons without evidence of multiple myeloma (MM), Waldenstrm's macroglobulinemia (WM), AL amyloidosis (AL), or other related diseases. MGUS is characterized by a seru...
MonoclonalGammopathyofUndetermined Significance(MGUS)and SmolderingMultipleMyeloma(SMM) Objectives •Definition •Diagnosticcriteria •EtiologyandPathogenesis •Diagnosticwork-up •Prognosticfactors •Patientmanagement Definition MGUSandSMMareasymptomaticplasmacellsdisordersthatareassociatedwithariskof progression...
Monoclonal gammopathy of undetermined significance (MGUS) is characterized by an M spike less than 3 g/dL and a bone marrow containing fewer than 10% plasma cells without evidence of CRAB (hypercalcemia, renal insufficiency, anemia, or bone lesions). Light chain MGUS has an abnormal free light...
1.Kyle RA, Durie BG, Rajkumar SV, Landgren O, Blade J, Merlini G, et al. Monoclonal gammopathy of undetermined significance (MGUS) and smoldering (asyntomatic) multiple myeloma: IMWG consensus perspectives risk factors progression and guidelines for monitoring and management. Leukemia 2010;24:1121...
In subject area: Pharmacology, Toxicology and Pharmaceutical Science formerly called benign monoclonal gammopathy) is a premalignant clonal plasma cell disorder characterized by the presence of a serum M protein in persons who lack evidence of multiple myeloma, macroglobulinemia, amyloidosis, or...
Monoclonal gammopathy of undetermined significance (MGUS): where is the hidden danger? Definition and work-up ArticleOpen access13 July 2020 Monoclonal Gammopathy of Undetermined Significance Chapter© 2018 Abbreviations AIHA: Autoimmune hemolytic anemia ...
The latter has been termed benign or nonmalignant monoclonal gammopathy , or monoclonal gammopathy of undetermined significance (MGUS). It is sometimes difficult to distinguish between the malignant and nonmalignant IgM monoclonal gammopathies, as serum IgM concentrations may remain constant for years, ...