In our study, miR-371a-3p levels in serum samples with proven disease recurrence were 13.65 fold higher than levels from the same patients without evidence of disease (p = 0.014). In contrast, miR-367 levels were not different in these patient groups (p = 0.985). In conclusion, miR-371...
In our study, miR-371a-3p levels in serum samples with proven disease recurrence were 13.65 fold higher than levels from the same patients without evidence of disease (p = 0.014). In contrast, miR-367 levels were not different in these patient groups (p = 0.985). In conclusion, miR-371...
We have provided the largest dataset of evaluation of CRIPTO in serum and seminal plasma of GCTs, showing its potential value as a biomarker of the disease. Keywords: CRIPTO; fertility; germ cells; germ cell tumors; miR-371a-3p; semen; serum; testicular cancer Cancers 2020, 12, 760; doi...
差异无统计学意义(F=1.547,P=0.246);20例NSCLC患者(腺癌10例,鳞状细胞癌10例)血清中有11例(55%)高表达miR-520d-3p.结论 2,4 Gy X线照射可提高A549细胞miR-520d-3p的体内,外表达水平,可能与增强A549细胞体内,外侵袭转移能力相关;NSCLC患者50%以上的血清样本中miR-520d-3p表达显著升高,可能作为NSCLC诊断的...
Methods: relative levels of miR-371a-3p, miR-373-3p and miR-367-3p were evaluated in serum of metastatic TGCC patients. A prospectively included and a retrospectively selected cohort were studied (total patient number = 109). Blood samples were drawn at start of chemotherapy and during follow...
Results and limitations Overall, miR-371a-3p performed best, with 88.7% sensitivity (95% confidence interval 82.5–93.3%) and 93.4% specificity (95% CI 86.9–97.3%) and an area under the curve of 0.94, outperforming AFP, bHCG, and LDH (combined sensitivity 50%). According to Kernel ...