MiR-381-3p suppresses biological characteristics of cancer in head-necksquamous cell carcinoma cells by targeting nuclear autoantigenic spermprotein (NASP)Fanyong Konga , Lianhe Li b , Chaoshan Wang a , Qiang Zhang cand Shizhi He da Department of Otolaryngology, Shunyi District Hospital of Beijing,...
目的探讨不同认知障碍程度和疗效的青少年抑郁症患者miR-381-3p、miR-124检测的临床意义。方法选取2020年1月至2022年4月绍兴市第七人民医院收治的86例青少年抑郁症患者为研究对象,其中存在认知障碍31例,包括轻度14例、中度12例和重度5例;无认知障碍55例。所有患者接受心理干预、认知疗法、重复经颅磁刺激疗法联合草酸艾...
、miR-381-3p降低，TXA2升高（P C0.05)。与BDNF、miR-381-3p、TXA2单一预测相比，联合预测对抑郁症使用乌灵 胶囊效果诊断效能较高（P<〇. 05)。结论抑郁症患者使用乌灵胶旗干预后，BDNF、miR-381-3p、TXA2表达异常，有效患者BDNF、miR-381-3p较高，TXA2较低，无效则相反，三者与乌灵胶囊效果的治疗效果具有...
结果miR-381-3p在食管癌细胞EC9706中低表达(P<0.01),而SP1高表达(P<0.01);miR-381-3p与SP13′UTR区存在结合位点,且miR-381-3p直接靶向抑制SP1表达;过表达miR-381-3p后,食管癌细胞增殖明显降低(P<0.01),Ki67和PCNA蛋白表达明显下调(P<0.01),细胞凋亡率明显降升高(P<0.01),Bax/Bcl-2和cleaved caspase-3...
Overexpression of miR-381-3p inhibited breast cancer proliferation and invasion, whereas knockdown of miR- 381-3p promoted cell proliferation and invasion in MDA-MB-231 and SKBR3 cells. Mechanistically, overexpression of miR-381-3p inhibited breast cancer epithelial–mesenchymal transition (EMT). Both...
MiR-381-3p and nuclear autoantigenic sperm protein (NASP) have regulatory functions in tumors. Whether NASP is targeted by miR-381-3p to influence biological characteristics of cancer in head-neck squamous cell carcinoma (HNSCC) cells was investigated. StarBase (version 3.0) found that the express...
结果miR-381-3p在食管癌细胞EC9706中低表达(P<0.01),而SP1高表达(P<0.01);miR-381-3p与SP13′UTR区存在结合位点,且miR-381-3p直接靶向抑制SP1表达;过表达miR-381-3p后,食管癌细胞增殖明显降低(P<0.01),Ki67和PCNA蛋白表达明显下调(P<0.01),细胞凋亡率明显降升高(P<0.01),Bax/Bcl-2和cleaved caspase-3...
miR-381-3p knockdown improves intestinal epithelial proliferation and barrier function after intestinal ischemia/reperfusion injury by targeting nurr1 Liwei Liu, Jihong Yao, Zhenlu Li, Guo Zu, Dongcheng Feng, Yang Li, Wasim Qasim, Su Zhang, Tong Li, Huizhi Zeng & Xiaofeng Tian ...
货号:mml-miR-381-3p 原价:￥4030 现价:￥3098.38节省:￥931.62 规格:1 kits 说明:mml-miR-381-3p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录...
To evaluate the effect of miR-381-3p on the differentiation of porcine intramuscular preadipocytes, cells were seeded in 12-well or 6-well plates and transfected, respectively, with negative control of miR-381-3p mimics (mimics-NC, n = 3), miR-381-3p mimics (n = 3), 100 pmol of neg...