www.nature.com/scientificreports OPEN received: 20 April 2015 accepted: 15 July 2015 Published: 10 August 2015 miR-378a-3p modulates tamoxifen sensitivity in breast cancer MCF-7 cells through targeting GOLT1A Kazuhiro Ikeda1, Kuniko Horie-Inoue1, Toshihide Ueno2, Takashi Suzuki3, ...
www.nature.com/scientificreports OPEN received: 20 April 2015 accepted: 15 July 2015 Published: 10 August 2015 miR-378a-3p modulates tamoxifen sensitivity in breast cancer MCF-7 cells through targeting GOLT1A Kazuhiro Ikeda1, Kuniko Horie-Inoue1, Toshihide Ueno2, Takashi Suzuki3, ...
For the detection of the role of miRNA in H/R-induced cells injury, the miR-182-5p mimics and miR-378a-3p mimics or inhibitor were transfected to cells 12 h before the H/R induction. The cells were detected the cell viability by using the Cell Counting Kit-8 cell viability kit ...
miR-378a-3p Targets NUAK2 to Inhibit Proliferation, Migration, and Invasion of Breast Cancer Cells[J]. Cancer Research on Prevention and Treatment, 2024, 51(6): 432-439. DOI: 10.3971/j.issn.1000-8578.2024.23.1216 Citation: CHEN Jianbin, WANG Tairen. miR-378a-3p Targets NUAK2 to ...
This study aims to elucidate the role of miR-378a-3p in facilitating the proliferation and differentiation of synovium-derived mesenchymal stem cells (SMSCs) into chondrocytes. The effects of overexpressing miR-378a-3p on SMSCs were investigated through histological analysis, quantitative PCR, and ...
miR-378a-3p;metformin;mitochondria;mitophagy;C2C12 1. Introduction Mitochondria are mostly known for their role as the main energy producers of most cells. Despite their role in aerobic respiration, they are also crucial for other important cellular processes, including cell metabolism regulation, calc...
Extracellular vesicles β-cell miR378a-3p Diabetes 1. Introduction Diabetes is one of the leading causes of death and disability worldwide, affecting people of all ages, both sexes, and all countries. It is estimated that more than 500 million people worldwide had diabetes, with a global age...
rats. Notably, knockdown of BMP2 diminished the reparative efficacy of miR-378a-3p on articular cartilage damage. Upregulation of miR-378a-3p promotes chondrogenic differentiation in SMSCs through activation of the BMP2-Smad pathway, positioning it as a potential therapeutic target for ...
网络药理学分析提示,miR-378a-3p与心肌缺血存在共同靶点且miR-378a-3p可能通过细胞凋亡和血管生成途径干预心肌缺血,有作为心肌缺血标志物的可能.动物实验证实miR-378a-3p表达量随心肌缺血时间变化逐渐上调且在6h时表达明显升高,且miR-378a-3p表达水平较cTnT更早在心肌缺血中出现高表达.临床数据分析表明,同健康对照...
MiR-378a-3p was upregulated in BL, and its inhibition reduced the growth of multiple BL cell lines. RNA immunoprecipitation of Argonaute 2 followed by microarray analysis (Ago2-RIP-Chip) upon inhibition and ectopic overexpression of miR-378a-3p revealed 63 and 20 putative miR-378a-3p ...