MiR-3529-3p was a significant differentially expressed miRNA between CAF-Exos and exosomes from hOMFs (hOMF-Exos). The overexpression of miR-3529-3p promoted proliferation, migration, and invasion and inhibited apoptosis of Cal-27 cells. Significance: This study explores the role of PDGF-BB-...
miR-3529-3p/ABCA1 axis regulates smooth muscle cell homeostasis by enhancing inflammation via JAK2/STAT3 pathwaydoi:10.3389/fcvm.2024.1441123Tingyu WangYou YuYinglong DingZiying YangShumin JiangFaxiong GaoShan LiuLianbo ShaoZhenya ShenFrontiers in Cardiovascular Medicine...
口腔鳞状细胞癌癌相关成纤维细胞外泌体miR-3529-3p[目的]癌相关成纤维细胞(CAFs)是肿瘤微环境中的重要基质细胞,与正常成纤维细胞相比,其处于功能极化状态,能促进肿瘤的恶性行为并与治疗效果密切相关.项目组前期研究发现,口腔鳞状癌细胞分泌的血小板衍生生长因子-BB(PDGF-BB)可活化人口腔粘膜成纤维细胞(hOMF)为CAFs,...