Here, we demonstrated miR-351-5p as a causative factor in hippocampal neural progenitor cell death through modulation of the mitochondrial GTPase, Miro2. Downregulation of Miro2 by siMiro2 induced cell death, similar to miR-351-5p, whereas ectopic Miro2 expression using an adenovirus abolished ...
Mir-351-5p contributes to the establishment of a pro-inflammatory environment in the H9c2 cell line by repressing PTEN expression 来自 国家科技图书文献中心 喜欢 0 阅读量: 9 作者:Souza,dos,Santos,Robson,Augusto,Moraes,Karen,C.,M.,da
目的探究褪黑素能否通过circPtpn14/miR-351-5p/5-LOX信号通路减轻铁死亡,从而保护血脑屏障. 方法将30只C57BL/6雄性小鼠随机分为假手术组,TBI组以及TBI+褪黑素治疗组,并通过CCI装置建立TBI模型,随后采用RNA-Seq技术筛选差异表达的circRNA.采用PCR和FISH对circPtpn14(mmu_circ_0000130)的性质进行鉴定.采用生物信息学...
本研究旨在探索TN模型中TG上Kv1.1和miR-21-5p的关系,评估miR-21-5p是否对Kv1.1有调控作用,为TN的治疗提供新的靶点。方法:将48只SD大鼠随机分为6组:1)假手术组(sham组,n=12),大鼠仅在术侧切口缝合,不结扎神经;2)Sham+agomir NC组(n=6),sham大鼠通过脑立体定位注射方法于术侧TG微量注射agomir NC;3)Sham...
CircFoxo3调节miR-130a-5p
The expression of molecules in the four potential ceRNA regulatory networks was detected by qRT-PCR in bronchial and lung tissues, and the results suggested that the expression of this regulatory network, chr9:52042693|52047844-miR-351-5p-Pten, was consist...
Furthermore, we also demonstrated that dioscin inhibited the expression level of miR-351-5p via reducing TRBP expression level during the generation of miR-351-5p mature body. Dioscin showed protective effect against II/R injury via adjusting miR- 351-5/Sirt6 signal to reduce oxidative stress, ...
miR-371-5p down-regulates pre mRNA processing factor 4 homolog B (PRPF4B) and facilitates the G1/S transition in human hepatocellular carcinoma (vol 335, pg 351, 2013) 来自 国家科技图书文献中心 喜欢 0 阅读量: 99 作者:RY Liu,CF Diao,Y Zhang,N Wu,HY Wan,XY Nong,M Liu,H Tang ...
Relative miRNA expression levels of miR-20b-5p, -212, -351 and miR-let-7f in the rat cortex following 5 or 10 days of hypoxia.Yilin, Yang
Yupeng HuZhang MaoLina XuLianhong YinXufeng TaoZeyao TangYan QiPengyuan SunJinyong Peng