The suppression of mitochondrial fission by Mdivi-1 completely inhibited cell death by miR-351-5p. miR-351-5p expression increased whereas the level of Miro2 decreased in the hippocampus of AD model mice, emulating expression in AD patients. Collectively, the data indicates the mitochondrial ...
Mir-351-5p contributes to the establishment of a pro-inflammatory environment in the H9c2 cell line by repressing PTEN expression 来自 国家科技图书文献中心 喜欢 0 阅读量: 11 作者:Souza,dos,Santos,Robson,Augusto,Moraes,Karen,C.,M.,da
目的探究褪黑素能否通过circPtpn14/miR-351-5p/5-LOX信号通路减轻铁死亡,从而保护血脑屏障. 方法将30只C57BL/6雄性小鼠随机分为假手术组,TBI组以及TBI+褪黑素治疗组,并通过CCI装置建立TBI模型,随后采用RNA-Seq技术筛选差异表达的circRNA.采用PCR和FISH对circPtpn14(mmu_circ_0000130)的性质进行鉴定.采用生物信息学...
骨髓间充质干细胞来源的外泌体通过miR-351-5p调控TRAF6对大鼠脊髓缺血再灌注损伤后细胞焦亡影响的研究 目的:脊髓缺血再灌注损伤(Spinal Cord Ischemia-reperfusion Injury,SCII)是胸腹主动脉等手术最严重的并发症之一,其发病率较高,可引起急性感觉障碍,如痛觉过敏和异常... 周泓旭 - 中国医科大学 被引量: 0发表:...
Chen等[11]研究发现miR-150-5p过表达促进HSC凋亡,miR-150-5p介导的干扰素信号通路的激活可能与HSC的凋亡有关致使肝细胞凋亡;Wu等[12]发现miR-140-3p通过调控pten介导的AKT/mTOR信号通路抑制HSC的增殖和纤维化;Wang等[13]发现miR-134...
MiR-361-5p has been proved to be a tumor suppressor in colorectal cancer and gastric cancer in our previous study. In this study, we aim to find out the function of miR-361-5p in breast cancer progression and elaborate the mechanism that miR-361-5p acts its function in breast cancer. ...
5p 376c 351 467d 337-3p 137 200b 342-5p 1944 381 592 674 153 191 1965 143 676 467c 669n 146b 7d 708 19b 19a 26b 495 296-5p 7i-3p 449a 203 1939 379 544 223 717530072--165330bpbp6-3b29p13137666c5-4325p1544991548123-55bp 135a 598 505 1893 466b-5p 136-3p –4 –3 –2 ...
(Figure 2A).The expression of several pro- or anti-fibrotic miRNAs was measured using qRT-PCR. Data indicated that TGFβ1 induced upregulation of pro-fibrotic miRNAs in FAPs, especially DNM3OS-associated miRNAs miR-214-3p and miR-199a-5p, while anti-fibrotic miRNAs, Let-7a and miR-29b,...
MicroRNA 199b-5p delivery through stable nucleic acid lipid particles (SNALPs) in tumorigenic cell lines. Naunyn Schmiedebergs Arch. Pharmacol. 2013, 386, 287–302. [Google Scholar] [CrossRef] [PubMed] Cui, X.; Song, K.; Lu, X.; Feng, W.; Di, W. Liposomal Delivery of MicroRNA-...
申请号:cn202210148718.x,发明名称:一种外泌体mirna在制备慢性疼痛-抑郁共病诊断产品中的应用,公开了一种外泌体mirna在制备慢性疼痛-抑郁共病诊断产品中的应用,所述外泌体mirna为血浆外泌体mir-351-5p。申请号:202210066968.9,发明名称:mirna-139-5p在制备预防或治疗抑郁症靶向药物中的应用,该发明公开mirna-139-...