而且,与 miR-362-3p 模拟物组相比,IFNα 联合 miR-362-3p 模拟物组降低了 -lgTCID50,并显著降低了 VP1 mRNA 和蛋白质的表达。结论:IFNα 诱导的 miR-362-3p 上调与抑制 EV71 感染的 HMC3 细胞复制相关,进而增强了抗病毒活力。
(P>0.05),提示siALDOA可以回复miR-362-3p inhibitor对喉癌细胞迁移的影响,表明miR-362-3p通过ALDOA影响喉癌细胞的迁移.结论:1,miR-362-3p在喉癌中发挥癌基因作用,其表达水平与喉癌恶性程度有关.2,miR-362-3p促进喉癌细胞的迁移.3,ALDOA可能是miR-362-3p的靶基因.4,miR-362-3p部分通过ALDOA促进喉癌Hep2细胞的...
英文名称: hsa-mir-362-3p Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit 品牌: Abbexa 货号: abx097787 规格: 50 rxns 价格: $493 产品说明书下载: 产品预定 >> 产品预定,提交订单信息之后,我们会第一时间与您取得联系 试剂和工具 试剂...
摘要目的:通过构建冠心病大鼠模型,探讨微小RNA-362-3p(miR-362-3p)是否通过调节有丝分裂原活性蛋白激酶1(MAPK1)㊁蛋白酪氨酸磷酸酶基因(PTEN)㊁蛋白激酶B(AKT),参与影响冠心病大鼠的心肌细胞凋亡和内皮细胞损伤㊂方法:构建冠心病大鼠模型,随即将大鼠分为健康组㊁冠心病组㊁miR-362过表达组㊁过表达阴性对照...
After miR-362-3p and CD82 were silenced in GC cells, we compared the transfected GC cells migration and invasion capacity by transwell assay. In addition, we detected the effects on cells angiogenesis by tube formation assay. Western blot was used to detect the impact of CD82 and miR-362-...
362-3p on cell proliferation, cell migration, and tumor metastasis in ovarian cancer. A luciferase reporter assay was performed to confirm the potential target of miR-362-3p, and a rescue experiment was employed to verify the effect of miR-362-3p on ovarian cancer by regulating its target ...
Higher miR-362-3p expression might independently predict favorable overall survival (OS) in SCC patients (HR: 0.561, 95%CI: 0.354−0.889, p = 0.014), after adjustment of clinical stages, lymphovascular invasion and miR-362-5p expression. However, no prognostic value of miR-362-5p or...
是miR-362-3p的潜在靶基因之一.研究表明,ALDOA在包括胰腺癌,肺癌,结肠癌,胃癌和肾癌等多种肿瘤中表达异常且与肿瘤细胞的迁移转移有关,然而,其在喉癌中表达和作用研究尚不清楚.本研究中,我们拟运用相关分子生物学技术检测miR-362-3p在喉癌中表达水平,临床意义及其对喉癌细胞迁移侵袭能力的影响,预测miR-362-3p的...
Finally, we analyzed correlations between miR-362-3p expression and clinicopathological characteristics and observed that miR-362-3p low expression was associated with advanced clinical stage and poor prognosis. In conclusion, miR-362-3p is a tumor suppressive miRNA in cervical adenocarcinoma. 展开 ...
目的:探讨miR-362-3p在胆囊癌中的表达及功能。 方法:用qRT-PCR检测手术切除的44例胆囊癌患者手术标本中miR-362-3p的表达,并分析其表达与胆囊癌临床病理特征及预后的关系。miR-362-3p模拟物转染胆囊癌细胞后,分别用MTT法、细胞划痕试验及Transwell侵袭试验观察细胞增殖、迁移及侵袭的改变。通过生物信息学方法及双荧光...