本发明证明了lifr是mir-196a-5p的靶向结合位点,mir-196a-5p过表达抑制lifr表达,mir-196a-5p低表达促进lifr表达。因此mir-196a-5p可以用于制备调控lifr表达的试剂。 技术特征: 1.mir-196a-5p在制备调控lifr表达的试剂中的应用。 2.如权利要求1所述的应用,其特征在于,mir-196a-5p过表达抑制lifr表达,mir-196...
MCE 国际站:hsa-miR-196a-5p inhibitor 产品活性:hsa-miR-196a-5p inhibitor 是一种全链经过甲氧基修饰的成熟miRNA的互补单链。miRNA inhibitor通过特异性结合成熟miRNA,阻止miRNA与其靶基因的互补配对,从而抑制miRNA的功能,可用于miRNA 功能缺失性(loss-of-function)研究。 研究领域:Epigenetics 作用靶点:MicroRNA ...
MiR-196a-5pBACH1HypertensionVascular remodelingOxidative stressHyperproliferation of vascular smooth muscle cells (VSMCs) is a driver of hypertensive vascular remodeling. This study aimed to uncover the mechanism of BTB and CNC homology 1 (BACH1) and microRNAs (miRNAs) in VSMC growth and ...
过表达或下调miR-196-5p在A431细胞中的表达后,通过CCK-8实验检测miR-196-5p对A431细胞增殖能力的影响;细胞侵袭实验检测miR-196-5p对A431细胞侵袭能力的影响;Western blot检测miR-196-5p对A431细胞内E-cadherin、N-cadherin表达的影响...
另试剂盒中提供一支RNA 酶DNA 酶free的双蒸水,可用于360次体系的配制。 本试剂盒目前订购,还可赠送内参的特异性引物试剂盒,该试剂盒包括检测该内参的qPCR上下游引物,以及逆转录使用的特异性茎环引物,该部分可以单独购买; 三部分可以分开订购:
The calculated Area under curve (AUC) levels showed that miR-196a-5p (AUC: 0.64; 95% CI: 0.521–0.759;=0.032) for obstructive CAD and STEMI groups, miR-373-3p (AUC: 708; 95% CI: 0.605–0.812;) for STEMI group and miR-375 (AUC: 0.722; 95% CI: 0.635–0.808;<) for obstructive...
hsa-mir-196a-5p Real-time RT-PCR Detection Kit 中文名: 中文别名: CBNumber: CB55996439 分子式: 分子量: 0 MOL File: Mol file 化学性质安全信息用途供应商1 hsa-mir-196a-5p Real-time RT-PCR Detection Kit化学性质 安全信息 hsa-mir-196a-5p Real-time RT-PCR Detection Kit性质、用途与生产工艺...
有研究发现miR-196a/b(miR-196a,miR-196b-5p)在皖南花猪中的表达水平最高,miR-196a/b通过一种新的途径影响猪背长肌中的脂肪发生脂肪细胞因子信号通路。目前,关于miR-133a的报道多集中影响细胞的增殖和分化,研究用于抑制癌症疾...
miR-196a-5p was correlated with CAG progression to GC. Overexpression of miR-196a-5p promoted GC cell proliferation and migration and inhibited apoptosis, whereas suppression of miR-196a-5p exerted the opposite effect. Based on the prediction and luciferase assays, ACER2 was identified as the ...
In pull-down assays, there was a 3.4- and 5.2-fold increase in miR-196a-5p (P = 0.054) and miR-196b-5p (P = 0.035), respectively, using the UGT2A1 3'-UTR biotinylated mRNA probe as compared with the β-actin coding region control mRNA probe. UGT2A1 mRNA was reduced by 25% ...